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Although Crohn\u2032s disease can affect the entire gastrointestinal tract\u2014from the mouth to the anus\u2014ulcerative colitis is limited to the colon and rectum. This report describes the case of a 16\u2010year\u2010old male patient who suffered from a painless, bilateral swelling of the lower lip persisting for 4 months. Elevated fecal calprotectin (510\u2009mg\/kg) and subsequent endoscopic examination confirmed the diagnosis of Crohn\u2032s disease. Immunosuppressive therapy led to full resolution of the lip swelling and overall clinical improvement. Oral manifestations such as ulcers, gingivitis, and angular cheilitis can be the first signs of a systemic disease, such as Crohn\u2032s disease in this case, and therefore provide an opportunity for early detection by general dentists.<\/jats:p>","DOI":"10.1155\/crid\/9912321","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T12:25:19Z","timestamp":1785932719000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bilateral Lower Lip Swelling as an Early Manifestation of Crohn\u2032s Disease in a 16\u2010Year\u2010Old Patient: A Case 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