{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:51:47Z","timestamp":1787313107908,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"vor","delay-in-days":204,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Introduction:<\/jats:bold>\n                    Mature cystic teratoma is a common benign ovarian germ cell tumor containing well\u2010differentiated cells from three germ layers. Malignant transformation within these teratomas, such as papillary thyroid carcinoma, is extremely rare.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Case Report:<\/jats:bold>\n                    A 62\u2010year\u2010old asymptomatic woman was found to have a 5\u2009cm hyperechoic lesion with an internal cystic component in her left ovary, suspected to be a mature teratoma. A total hysterectomy with bilateral salpingo\u2010oophorectomy was performed, removing an unruptured, thin\u2010walled ovarian tumor. Gross pathology revealed a uni\u2010loculated solid\u2010cystic lesion with smooth serosa, a homogenous tan solid part containing soft tan hair, and no papillary projections, adhesions, or ascites. Pathology identified a 2\u2009cm papillary thyroid carcinoma (classic subtype) arising in a 4.7\u2009cm mature teratoma, without lymphovascular invasion or ovarian surface involvement. Thyroid ultrasound, thyroid function tests, and PET imaging showed no abnormalities or metastasis. The role for total thyroidectomy and radioactive iodine ablation was discussed. After reviewing the pathology and confirming the absence of aggressive tumor behavior, shared decision\u2010making led to opting against further treatment. Three years postoperatively, there was no recurrence or metastasis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    This case describes the rare occurrence of papillary thyroid carcinoma within a mature ovarian teratoma. Currently, there is a lack of consensus on postoperative management. In selected cases with no evidence of metastasis or aggressive features, conservative management may be a reasonable option after thorough evaluation.\n                  <\/jats:p>","DOI":"10.1155\/crie\/7914933","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T14:18:38Z","timestamp":1753366718000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Papillary Thyroid Carcinoma Arising Within a Mature Ovarian Cystic Teratoma: A Case Report"],"prefix":"10.1155","volume":"2025","author":[{"given":"Pakaworn","family":"Vorasart","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5218-5041","authenticated-orcid":false,"given":"Rangsima","family":"Aroonroch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7778-6924","authenticated-orcid":false,"given":"Naparat","family":"Rermluk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9980-007X","authenticated-orcid":false,"given":"Orawin","family":"Vallibhakara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8294-8601","authenticated-orcid":false,"given":"Chutintorn","family":"Sriphrapradang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,24]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2019.06.025"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2022.07.004"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-020-02873-0"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(99)00141-4"},{"key":"e_1_2_13_5_2","first-page":"22","article-title":"Mature Cystic Teratoma: A Clinicopathologic Evaluation of 517 Cases and Review of the Literature","volume":"84","author":"Comerci J. 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