{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T05:18:11Z","timestamp":1788239891347,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":242,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Genetics"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Mosaicism for both a ring chromosome and Robertsonian translocation is a rarely reported cytogenetic phenomenon. We describe a case referred for testing following abnormal noninvasive prenatal screening for trisomy 13. Prenatal chromosomal microarray (CMA) testing identified a mosaic 3.6\u2010Mb terminal loss in 13q34, which was confirmed by postnatal CMA. At birth, the phenotype included a small head circumference (3rd percentile) and a patent ductus arteriosus. Conventional chromosome analysis identified mosaicism of two abnormal cell lines, one containing der(13;21)(q10;q10) and the other containing r(13)(p11.2q33). This case demonstrates the utility of conventional chromosomal analysis following an abnormal CMA result.<\/jats:p>","DOI":"10.1155\/crig\/7026115","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T04:47:52Z","timestamp":1788238072000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Finding of Mosaic 45,XX,der(13;21)(q10;q10)[15]\/46,XX,r(13)(p11.2q33) Following Abnormal Prenatal Chromosomal Microarray Testing"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0021-1409","authenticated-orcid":false,"given":"Katherine M.","family":"Haines","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah M.","family":"Hazard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4197-6495","authenticated-orcid":false,"given":"Billie","family":"Carstens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter M.","family":"Brzeskiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Gilfillan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3548-3151","authenticated-orcid":false,"given":"Hala","family":"Nijmeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandra","family":"Perez-Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikayla","family":"Stoecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5337-5090","authenticated-orcid":false,"given":"Farrah","family":"Rajabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary M.","family":"Haag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5845-226X","authenticated-orcid":false,"given":"Stephen J.","family":"Wicks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2017.91"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature14135"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-023-02578-6"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-022-02444-x"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10577-014-9439-3"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.36.1.77"},{"key":"e_1_2_9_7_2","first-page":"113","article-title":"Trisomy\/Partial Monosomy 13 Mosaicism Associated With Relatively Mild Clinical Malformation","volume":"35","author":"Duckett D. 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An Analysis of 207 Case Reports on Patients With a Ring Autosome","volume":"75","author":"Kosztol\u00e1nyi G.","year":"1987","journal-title":"Human Genetics"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-019-02048-y"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2012.01.083"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5931"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm3030809"}],"container-title":["Case Reports in Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crig\/7026115","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crig\/7026115","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crig\/7026115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T04:47:57Z","timestamp":1788238077000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crig\/7026115"}},"subtitle":[],"editor":[{"given":"Neetu","family":"Rawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crig\/7026115"],"URL":"https:\/\/doi.org\/10.1155\/crig\/7026115","archive":["Portico"],"relation":{},"ISSN":["2090-6544","2090-6552"],"issn-type":[{"value":"2090-6544","type":"print"},{"value":"2090-6552","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-03-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"7026115"}}