{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:49:50Z","timestamp":1782125390103,"version":"3.54.5"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":172,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Immunology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Dragon fruit, also known as pitahaya, has become increasingly popular in Europe and the United States owing to its nutritional value and potential health\u2010promoting properties. This study describes a patient with anaphylaxis after the ingestion of dragon fruit. We present the case of a patient who experienced a systemic reaction requiring hospitalization 1\u2009h after consuming dragon fruit. His medical history includes allergic rhinitis to\n                    <jats:italic>Salsola kali<\/jats:italic>\n                    pollen. The diagnostic worked\u2010up included prick\u2010by\u2010prick testing with fruits, skin prick testing with aeroallergens, and measurement of specific IgE using ImmunoCAP and ISAC. These tests confirmed sensitization to dragon fruit, several pollens including\n                    <jats:italic>S. kali<\/jats:italic>\n                    , and peach allergens. A protein extract was prepared from dragon fruit pulp. In the protein profile, the most intense bands were observed at 9, 26, and 54\u2009kDa. The patient\u2019s IgE recognized multiple bands ranging from 16 to &gt;100\u2009kDa. Immunoblot inhibition demonstrated cross\u2010reactivity:\n                    <jats:italic>S. kali<\/jats:italic>\n                    extract almost completely inhibited IgE recognition of dragon fruit proteins, leaving only faint recognition of a 54\u2010kDa band (identified as catalase), while peach peel extract completely inhibited IgE binding to the dragon fruit extract. In conclusion, sensitization to dragon fruit in this patient was probably due to cross\u2010reactivity with\n                    <jats:italic>S. kali<\/jats:italic>\n                    and peach allergens. This case highlights the potential risks associated with the introduction of novel foods into the diet, particularly in patients previously sensitized to pollen or other plant\u2010derived foods.\n                  <\/jats:p>","DOI":"10.1155\/crii\/5321048","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:09:19Z","timestamp":1782122959000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dragon Fruit Allergy With Cross\u2010Reactivity to\n                    <i>Salsola kali<\/i>\n                    and Peach"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4931-6749","authenticated-orcid":false,"given":"Luc\u00eda","family":"Ferrer 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