{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T08:05:08Z","timestamp":1779955508156,"version":"3.53.1"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":147,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Immunology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Guillain\u2010Barr\u00e9 syndrome (GBS) is a rare autoimmune disorder characterized by peripheral nerve involvement. Among the many kinds of GBS, acute motor axonal neuropathy (AMAN) syndrome has been shown to have distinct clinical characteristics and consequences. Meanwhile, ankylosing spondylitis (AS) is a long\u2010term inflammatory joint illness that mostly affects the sacroiliac joints and the spine; this disorder has been known to cause discomfort and stiffness, which may lead to decreased flexibility over time. Some studies have found a link between anti\u2010TNF \u03b1 medication and GBS. GBS was commonly related to anti\u2010TNF\u2010\u03b1 treatment for established AS, which explains the rare overlap of both diseases. In our case, nevertheless, both conditions occurred together without any confirmed therapeutic or infectious provocation. We describe a case of a 35\u2010year\u2010old painter hospitalized with paralysis of the lower and upper limbs but normal reflexes. Electromyography (EMG) demonstrated axonal motor neuropathy, and a lumbar puncture revealed high protein levels (42.2\u2009mg\/dL) and a normal cell count, all of which are indicators of GBS; hence, he was diagnosed with AMAN. Additional testing revealed human leukocyte antigen (HLA)\u2010B27 positive and bilateral sacroiliitis on magnetic resonance imaging (MRI), which is consistent with AS. The administration of plasma exchange (PLEX) treatment improved the bulbar function.<\/jats:p>","DOI":"10.1155\/crii\/5406702","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T07:41:21Z","timestamp":1779954081000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acute Motor Axonal Neuropathy Coexisting With Ankylosing Spondylitis: A Case\u2010Based Review"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6954-5215","authenticated-orcid":false,"given":"Yi\u011fit Can","family":"G\u00fcldiken","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3918-8792","authenticated-orcid":false,"given":"Batool","family":"Achmar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5706-4943","authenticated-orcid":false,"given":"Sema","family":"Kaymaz Tahra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2013.01.005"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000038890"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2017.6248"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-014-0489-6"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-205253"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2007.06.021"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-021-05679-7"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.5312\/wjo.v2.i12.107"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-0968.2004.00183.x"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-017-3573-1"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-1999-217"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-205124.92"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-009-1154-7"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.4081\/reumatismo.2019.1115"},{"key":"e_1_2_9_15_2","article-title":"Bickerstaff Brainstem Encephalitis in a Patient With Ankylosing Spondylitis on Tumour Necrosis Factor-Alpha Inhibitor","volume":"36","author":"Kim M.","year":"2018","journal-title":"Clinical and Experimental Rheumatology"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.88374"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000392"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2016.1193006"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcaa018"},{"key":"e_1_2_9_20_2","unstructured":"National Institute of Neurological Disorders and Stroke Amyotrophic Lateral Sclerosis (ALS) https:\/\/www.ninds.nih.gov\/health-information\/disorders\/amyotrophic-lateral-sclerosis-als?search-term=Amyotrophic%20Lateral%20Sclerosis%20(ALS)#toc-who-is-more-likely-to-get-amyotrophic-lateral-sclerosis-als-."},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/ene.16073"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14393"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.051136"},{"key":"e_1_2_9_24_2","unstructured":"Amyotrophic Lateral Sclerosis 2025 PubMedhttps:\/\/pubmed.ncbi.nlm.nih.gov\/32310611\/."},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1114525"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.4103\/1817-1745.92844"},{"key":"e_1_2_9_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1980.00500570059009"},{"key":"e_1_2_9_28_2","doi-asserted-by":"publisher","DOI":"10.1177\/1756286418809580"},{"key":"e_1_2_9_29_2","unstructured":"Acute Motor Axonal Neuropathy Enterovirus and Amyotrophic Lateral Sclerosis: can There be a Link? 2003 PubMedhttps:\/\/pubmed.ncbi.nlm.nih.gov\/12618659\/."},{"key":"e_1_2_9_30_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8875666"},{"key":"e_1_2_9_31_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2002.00099.x"},{"key":"e_1_2_9_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-020-00908-2"},{"key":"e_1_2_9_33_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/327315"},{"key":"e_1_2_9_34_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-010-8213-3"},{"key":"e_1_2_9_35_2","doi-asserted-by":"publisher","DOI":"10.1159\/000351248"},{"key":"e_1_2_9_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780220716"},{"key":"e_1_2_9_37_2","unstructured":"Frequency of Atlantoaxial Subluxation and Neurologic Involvement in Patients With Ankylosing Spondylitis 1995 PubMedhttps:\/\/pubmed.ncbi.nlm.nih.gov\/8596154\/."},{"key":"e_1_2_9_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410330402"}],"container-title":["Case Reports in Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crii\/5406702","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crii\/5406702","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crii\/5406702","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T07:41:28Z","timestamp":1779954088000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crii\/5406702"}},"subtitle":[],"editor":[{"given":"Xingliang","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crii\/5406702"],"URL":"https:\/\/doi.org\/10.1155\/crii\/5406702","archive":["Portico"],"relation":{},"ISSN":["2090-6609","2090-6617"],"issn-type":[{"value":"2090-6609","type":"print"},{"value":"2090-6617","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-10-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5406702"}}