{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T21:03:13Z","timestamp":1773781393838,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":239,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Immunology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>IgG4\u2010related disease (IgG4\u2010RD) is a rare, progressive, and immune\u2010mediated fibroinflammatory disorder that primarily affects middle\u2010aged men and is more prevalent in Asian populations. Although extensively studied, its pathophysiology remains incompletely understood. This case report describes a 44\u2010year\u2010old male presenting with multiple abscesses and progressive inflammatory symptoms, ultimately diagnosed with IgG4\u2010RD with musculoskeletal involvement. Imaging and histopathological evaluation confirmed osteolytic lesions and significant IgG4\u2010positive plasma cell infiltration. Soft tissue tumors in IgG4\u2010RD are exceptionally rare, further emphasizing the uniqueness of this case. The patient showed clinical improvement with corticosteroid therapy. This case highlights the importance of considering IgG4\u2010RD in the differential diagnosis of soft tissue and bone lesions and underscores the need for a multidisciplinary diagnostic approach.<\/jats:p>","DOI":"10.1155\/crii\/6543528","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:06:27Z","timestamp":1756379187000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["IgG4\u2010Related Disease Inflamatory Pseudotumor Affecting the Sternoclavicular Joint: A Clinical Challenge"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4075-5761","authenticated-orcid":false,"given":"Orivaldo Alves","family":"Barbosa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talita Guimar\u00e3es","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio Saldanha Freire","family":"Sim\u00f5es","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre Luis Coutinho de Ara\u00fajo","family":"Macedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dower Frota","family":"Barroso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Paulo Uchoa","family":"Fontenele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Walter","family":"Correia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,28]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1067"},{"key":"e_1_2_9_2_2","doi-asserted-by":"crossref","unstructured":"HamanoH. KawaS. andHoriuchiA. et al.High Serum IgG4 Concentrations in Patients with Sclerosing Pancreatitis New England Journal of Medicine 2001 344 no. 10 732\u2013738 https:\/\/doi.org\/10.1056\/NEJM200103083441005 2-s2.0-0035826083.","DOI":"10.1056\/NEJM200103083441005"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2016.12.008"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2023-223950"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1104650"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.41465"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-52542-6"},{"key":"e_1_2_9_8_2","article-title":"IgG4-Related Disease Presenting as a Soft Tissue Tumor Affecting Skeletal Muscle: A Case Report","author":"S\u00e1ez Mart\u00ednez D.","journal-title":"International Journal of Clinical Medicine"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2017.10.005"},{"key":"e_1_2_9_10_2","first-page":"1201","volume-title":"Internal Medicine","author":"Hamano H.","year":"2018"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-007-0397-7"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejr.2021.08.004"}],"container-title":["Case Reports in Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crii\/6543528","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crii\/6543528","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crii\/6543528","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T17:40:10Z","timestamp":1773769210000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crii\/6543528"}},"subtitle":[],"editor":[{"given":"Suraiya","family":"Saleem","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crii\/6543528"],"URL":"https:\/\/doi.org\/10.1155\/crii\/6543528","archive":["Portico"],"relation":{},"ISSN":["2090-6609","2090-6617"],"issn-type":[{"value":"2090-6609","type":"print"},{"value":"2090-6617","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-04-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6543528"}}