{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T21:04:43Z","timestamp":1773781483680,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T00:00:00Z","timestamp":1739145600000},"content-version":"vor","delay-in-days":40,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Nephrology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Introduction:<\/jats:bold>\n                    Tuberculosis (TB) is a prevalent disease in Guatemala, present in 20\u201325 cases per 100 thousand inhabitants. Extrapulmonary TB (EPTB) accounts for only 10%\u201317% of TB cases. The diagnosis of EPTB is challenging, especially in low\u2010resource settings, because TB can present with clinical characteristics of rheumatological, oncological, or other infectious diseases. Occasionally, mycobacterial infection stimulates the immune system, inducing the generation of antibodies that may lead to autoimmune diseases secondary to primary TB infection, such as vasculitis. To the best of our knowledge, no data have been reported on the prevalence of vasculitis, although some studies worldwide have determined that small\u2010vessel vasculitis is the most common. Here, we present a case report of a male patient with EPTB diagnosed with\n                    <jats:italic>Microscopic polyangiitis<\/jats:italic>\n                    (MPA).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    A 17\u2010year\u2010old boy with no past medical history visited the emergency room with a three\u2010day history of gastrointestinal bleeding. During hospitalization, acute kidney injury (AKI), disseminated lymphadenopathy, imaging studies, renal biopsy, and immunological tests were performed to confirm the diagnosis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Endoscopy revealed a duodenal lesion containing\n                    <jats:italic>Mycobacterium TB<\/jats:italic>\n                    DNA. Further investigation of AKI led to autoimmune serological tests and kidney biopsy, confirming the diagnosis of antineutrophil cytoplasmic antibodies (ANCA)\u2013positive pauci\u2010immune GN. The patient was treated with antituberculous agents, steroids, and plasmapheresis. However, he developed alveolar hemorrhage and respiratory failure leading to death.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    TB is a common disease in low\u2010income countries, with the pulmonary form being the most common presentation; however, the bacteria can spread to any organ, known as EPTB. It is important to consider that the inflammatory reaction associated with any form of TB can generate other types of noninfectious inflammatory diseases, such as ANCA\u2013positive pauci\u2010immune GN.\n                  <\/jats:p>","DOI":"10.1155\/crin\/6619761","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T02:21:44Z","timestamp":1739240504000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Microscopic polyangiitis<\/i>\n                    With Pauci\u2010Immune Glomerulonephritis Associated With Gastrointestinal Tuberculosis"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1782-4893","authenticated-orcid":false,"given":"Alexis","family":"Monroy-Portillo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0535-9736","authenticated-orcid":false,"given":"Nancy","family":"Vargas-San Jos\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6446-9280","authenticated-orcid":false,"given":"Werner","family":"De Le\u00f3n-Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5071-5475","authenticated-orcid":false,"given":"Rodolfo","family":"Moreno-Alvarado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,10]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jctube.2021.100287"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-220777"},{"key":"e_1_2_10_3_2","first-page":"44","article-title":"Implementation of the National Tuberculosis Guidelines on Culture and Drug Sensitivity Testing in Guatemala, 2013","volume":"39","author":"Samayoa-Pel\u00e1ez M.","year":"2016","journal-title":"Revista Paname\u00f1a de Salud P\u00fablica"},{"key":"e_1_2_10_4_2","volume-title":"Global Tuberculosis Report 2018","year":"2018"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/jor1020015"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24065202"},{"key":"e_1_2_10_7_2","article-title":"Pathogenesis of Antineutrophil Cytoplasmic Autoantibody-Mediated Disease","volume":"11","author":"Charles Jennette J.","year":"2014","journal-title":"Nature Reviews"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.2215\/cjn.02500317"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2010.06.001"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2010.07.009"},{"key":"e_1_2_10_11_2","volume-title":"Caracterizaci\u00f3n Epidemiol\u00f3gica, Cl\u00ednica y Terape\u00fatica de Pacientes con Diagn\u00f3stico de Vasculitis [Tesis]","author":"Gir\u00f3n Delgado I. 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