{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T14:48:39Z","timestamp":1772981319223,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"vor","delay-in-days":55,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pathology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Perivascular epithelioid cell tumors (PEComas) of the uterus are rare mesenchymal neoplasms characterized by myogenic and melanocytic differentiation. These tumors can mimic other uterine mesenchymal tumors in their clinical presentation and morphology. We report a case of a 58\u2010year\u2010old woman who presented with abnormal uterine bleeding. Initial imaging revealed an endometrial polyp, which was later diagnosed as a leiomyoma on excision biopsy. A subsequent hysterectomy with bilateral salpingectomy revealed a uterine neoplasm composed of spindled to epithelioid cells with low\u2010grade cytologic atypia, infiltrative edges, and extensive lymphovascular invasions, initially suggestive of low\u2010grade endometrial stromal sarcoma. However, immunohistochemical stains demonstrated tumor positivity for HMB45, desmin, and Cathepsin K, and genetic testing revealed a\n                    <jats:italic>TSC1<\/jats:italic>\n                    variant, leading to a definite diagnosis of uterine PEComa with lymphangioleiomyomatosis (LAM)\u2010like features. The patient\u2032s postoperative course was uneventful, and follow\u2010up imaging showed no evidence of metastatic disease. This case highlights the importance of integrated morphological, immunohistochemical, and molecular assessment in differentiating uterine mesenchymal neoplasms to guide appropriate clinical management.\n                  <\/jats:p>","DOI":"10.1155\/crip\/1620175","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T08:15:34Z","timestamp":1772957734000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Uterine PEComa With Lymphangioleiomyomatosis (LAM)\u2010Like Features: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"given":"Ramani","family":"Raman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8113-243X","authenticated-orcid":false,"given":"Daisy","family":"Maharjan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5214-4813","authenticated-orcid":false,"given":"Carina","family":"Dehner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila","family":"Segura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199609000-00012"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gore.2020.100603"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000173232.22117.37"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000510241"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyaf056"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001119"},{"key":"e_1_2_10_7_2","unstructured":"Caris Life Sciences MI Cancer Seek 2024 https:\/\/www.carislifesciences.com\/physicians\/physician-tests\/mi-cancer-seek\/."},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-024-07510-5"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000014072"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.22908"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000133"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199005000-00002"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath-2015-202945"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000002218"},{"key":"e_1_2_10_15_2","volume-title":"WHO Classification of Tumours","author":"Bennett J.","year":"2022"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgc.2025.102002"}],"container-title":["Case Reports in Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crip\/1620175","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crip\/1620175","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crip\/1620175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T08:15:35Z","timestamp":1772957735000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crip\/1620175"}},"subtitle":[],"editor":[{"given":"Suraiya","family":"Saleem","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crip\/1620175"],"URL":"https:\/\/doi.org\/10.1155\/crip\/1620175","archive":["Portico"],"relation":{},"ISSN":["2090-6781","2090-679X"],"issn-type":[{"value":"2090-6781","type":"print"},{"value":"2090-679X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-08-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1620175"}}