{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T09:03:17Z","timestamp":1779872597870,"version":"3.53.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":146,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pathology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Ovarian carcinosarcoma typically comprises high\u2010grade carcinoma and sarcoma components. We report a case of a woman in her 40s with endometriosis\u2010associated ovarian carcinosarcoma exhibiting an unusual presentation of well\u2010differentiated adenocarcinoma and rhabdomyosarcoma. The patient underwent bilateral salpingo\u2010oophorectomy and hysterectomy for tumors in both ovaries. Histologically, with a background of endometriosis, the epithelial component exhibited features of a borderline tumor with an intraepithelial carcinoma composed of M\u00fcllerian\u2010type epithelium in both ovaries. In the left ovary, a very minor area of clear cell carcinoma (less than 5%) was identified. In contrast, the mesenchymal component was a well\u2010differentiated rhabdomyosarcoma resembling fetal rhabdomyoma, constituting more than 60% of the left ovarian tumor. One year later, pulmonary metastases of the sarcomatous component were detected. Molecular analysis using next\u2010generation sequencing identified\n                    <jats:italic>PIK3CA<\/jats:italic>\n                    H1047R (c.3140A &gt; G) and\n                    <jats:italic>CSF1R<\/jats:italic>\n                    (c.\u22171841TG &gt; GA) in both the epithelial and mesenchymal components, indicating a clonal origin and supporting a diagnosis of primary ovarian carcinosarcoma. The patient died 29 months after surgery despite receiving platinum\u2010based chemotherapy. This report highlights the challenges of diagnosing rare ovarian carcinosarcomas arising in endometriosis and with unusually low\u2010grade histology, and it emphasizes the need for comprehensive pathological assessment, including molecular analysis, for accurate diagnosis and optimal management.\n                  <\/jats:p>","DOI":"10.1155\/crip\/6781988","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T08:22:37Z","timestamp":1779870157000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Endometriosis\u2010Associated Ovarian Carcinosarcoma Featuring Well\u2010Differentiated Adenocarcinoma and Fetal Rhabdomyoma\u2010Like Mesenchymal Components: An Unusual Case Report\u2014With Molecular Analysis"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0346-6220","authenticated-orcid":false,"given":"Yuri","family":"Narusawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2697-114X","authenticated-orcid":false,"given":"Shiho","family":"Asaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsutomu","family":"Muramoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8245-7439","authenticated-orcid":false,"given":"Saori","family":"Konno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiko","family":"Kusama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7694-9015","authenticated-orcid":false,"given":"Takeshi","family":"Uehara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"e_1_2_10_1_2","volume-title":"Female 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