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Rarely, components other than cells and tissue fragments may be visualized upon microscopic scrutiny following biopsy. These findings may lead to confusion in diagnosis. We describe two cases in which refractile foreign materials caused diagnostic challenges. The material in the first case turned out to be barium crystals left at a prior procedure for imagining study. The material in the second case was most likely starch\u2010based material the patient aspirated or inhaled. These two cases highlight the importance of attention to details and judicious use of polarized microscopy.<\/jats:p>","DOI":"10.1155\/crip\/7005824","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T08:48:46Z","timestamp":1745484526000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unusual Findings With Imaging\u2010Guided Fine Needle Aspiration"],"prefix":"10.1155","volume":"2025","author":[{"given":"Robert","family":"Pei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shane M.","family":"Woods","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1329-1586","authenticated-orcid":false,"given":"Brant G.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1002\/deo2.388"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2013.07.029"},{"key":"e_1_2_8_3_2","first-page":"737","article-title":"Cytologic Diagnosis of Intravenous Talc Granulomatosis by Fine Needle Aspiration Biopsy. 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