{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T21:08:44Z","timestamp":1773781724370,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"vor","delay-in-days":355,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pathology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Collision tumors are rare neoplasms composed of two histologically distinct components without a transitional zone. Only nine cases involving periampullary adenocarcinoma and neuroendocrine tumor (NET) have been reported. A 55\u2010year\u2010old male presented with recurrent fever and jaundice. Imaging and biopsy revealed a periampullary lesion diagnosed as tubule\u2010villous adenoma with high\u2010grade dysplasia. He underwent pylorus\u2010preserving pancreatoduodenectomy. Histology revealed moderately differentiated intestinal\u2010type adenocarcinoma (pT2N1) with regional lymph node metastasis. Additionally, a 2\u2010mm well\u2010differentiated NET was found 2.5\u2009cm proximal to the primary tumor, also with nodal metastasis. Immunohistochemistry confirmed distinct lineages, fulfilling the criteria for a collision tumor. This case represents a rare periampullary collision tumor with both adenocarcinoma and NET components showing independent lymph node metastases. The absence of transitional zones rules out MiNEN. This report underscores the importance of thorough pathological assessment and adds to the limited literature on the behavior and prognosis of periampullary collision tumors.<\/jats:p>","DOI":"10.1155\/crip\/7777605","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T15:51:02Z","timestamp":1766418662000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case of Collision Tumor at the Periampullary Region"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6514-672X","authenticated-orcid":false,"given":"Kshitija","family":"Kale","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikram","family":"Chaudhari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0067-4748","authenticated-orcid":false,"given":"Vikas","family":"Ostwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shailesh V.","family":"Shrikhande","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6338-8191","authenticated-orcid":false,"given":"Kedar","family":"Deodhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"e_1_2_8_1_2","first-page":"104","volume-title":"WHO Classification of Tumours. 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