{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T21:09:40Z","timestamp":1773781780971,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":327,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100012921","name":"Royal College of Surgeons in Ireland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012921","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Surgery"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Breast implant associated anaplastic large cell lymphoma (BIA\u2010ALCL) is an uncommon form of non\u2010Hodgkin\u2019s T\u2010cell lymphoma associated with textured breast implants and tissue expanders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 46\u2010year\u2010old female presented with a 1\u2010week history of a firm lump in the upper inner quadrant of her right breast. She had a history of augmentation mammoplasty with textured implants 8 years prior. Ultrasound guided biopsy of the 15\u2009mm\u2009\u00d7\u200918\u2009mm mass confirmed a diagnosis of BIA\u2010ALCL on histopathology. Pre\u2010operative staging with PET CT showed a peri\u2010implant nodule with avid nodules within and deep to the pectoralis muscle with no evidence of distant metastases. Bilateral en bloc removal of the breast implants, capsulectomy (including palpably involved pectoralis major and minor muscles) and right axillary dissection were performed. Final histopathology confirmed BIA\u2010ALCL, pT4N0, with clear margins. Post\u2010operative PET\u2010CT demonstrated complete excision of local disease, however, a new FDG\u2010avid right internal mammary node was identified, which increased in size and avidity on follow up imaging. Mediastinoscopy with core biopsy were performed and histopathological features were consistent with metastatic cells (BIA\u2010ALCL). Patient subsequently completed six cycles of adjuvant chemotherapy with evidence of interval response on imaging. To date, patient remains in complete clinical and radiological remission and the expected duration of follow up is 5 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>BIA\u2010ALCL poses a significant challenge due to increasing use of implants for reconstructive and cosmetic procedures. Patients most commonly present with peri\u2010implant fluid collections but palpable masses, capsular contracture and lymphadenopathy are also commonly seen. Diagnosis involves ultrasound and histopathological analysis of fluid or tissue with CD30 immunohistochemistry and staging with PET\u2010CT. Patient education and a multidisciplinary team approach allow for timely diagnosis and complete surgical excision, which are key for a good prognosis. Clinical and radiological surveillance detect early recurrence and assess need for adjuvant therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/cris\/1393257","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T08:14:17Z","timestamp":1763972057000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anaplastic Large Cell Lymphoma Related to Breast Implant Presenting as a Solid mass: A Case Report"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1771-4822","authenticated-orcid":false,"given":"Nadia Gabriele","family":"Walsh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Hembrecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sally","family":"McGrath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deirdre","family":"Duke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnold","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Quinn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neasa Ni","family":"Mhuircheartaigh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"McKenna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colm","family":"Power","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,24]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2020.03.06"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199708000-00065"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-01-643569"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.21037\/abs-20-96"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2020.101963"},{"key":"e_1_2_7_6_2","unstructured":"American Society of Plastic Surgeons BIA-ALCL Physician Resources 2024 from American Society of Plastic Surgeonshttps:\/\/www.plasticsurgery.org\/for-medical-professionals\/health-policy\/bia-alcl-physician-resources."},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpra.2022.09.007"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.21037\/map-24-ab141"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-023-03445-z"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2009.01.010"},{"key":"e_1_2_7_11_2","volume-title":"TNM Classification of Malignant Tumours","author":"Brierley J. 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