{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T11:42:00Z","timestamp":1792496520702,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"vor","delay-in-days":292,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Surgery"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Buschke\u2010L\u00f6wenstein tumor (BLT) is a rare, locally aggressive anogenital tumor associated predominantly with low\u2010risk human papillomavirus (HPV) types 6 and 11. BLT is classically described as a slow\u2010growing lesion predominantly affecting middle\u2010aged men who are immunocompromised; cases of rapid progression are rarely reported. We present the case of a 23\u2010year\u2010old male with a progressively enlarging perianal mass over 1 year that was accompanied by rectal pain and intermittent bleeding. He reported prior unprotected heterosexual intercourse, though serologic testing for HIV, syphilis, and hepatitis B\/C was negative. CT imaging revealed a fungating lesion entirely distal to the dentate line without evidence of internal extension. Subsequently, the patient underwent wide local excision with electrocautery fulguration, and the wound was managed with healing by secondary intention. Histopathology revealed clear margins around a low\u2010grade squamous intraepithelial lesion (LSIL) without high\u2010grade dysplasia or carcinoma; in situ hybridization (ISH) confirmed HPV types 6 and 11, without detection of high\u2010risk HPV. A review of the literature on BLT epidemiology, histopathology, differential diagnosis, and management is presented. This case illustrates that BLT can progress rapidly in young, immunocompetent individuals and highlights that healing by secondary intention following wide local excision is a viable option in appropriately selected cases.<\/jats:p>","DOI":"10.1155\/cris\/4587993","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T10:58:16Z","timestamp":1792493896000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rapidly Progressive Buschke\u2010L\u00f6wenstein Tumor Managed With Wide Local Excision and Healing by Secondary Intention: A Case Report and Literature Review"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3521-2054","authenticated-orcid":false,"given":"Sabrina E.","family":"Chin","sequence":"first","affiliation":[{"name":"Department of Colon and Rectal Surgery Jackson South Medical Center  Miami Florida USA"},{"name":"Department of Surgery School of Medicine St. George\u2019s University  True Blue Grenada  sgu.edu"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2265-7829","authenticated-orcid":false,"given":"Natalia Rojas","family":"Castro","sequence":"additional","affiliation":[{"name":"Department of Colon and Rectal Surgery Jackson South Medical Center  Miami Florida USA"},{"name":"School of Medicine and Health Sciences University of Rosario  Bogot\u00e1 Colombia  urosario.edu.co"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2336-016X","authenticated-orcid":false,"given":"Henry J.","family":"Lujan","sequence":"additional","affiliation":[{"name":"Department of Colon and Rectal Surgery Jackson South Medical Center  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,20]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1687835"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/jpm14080887"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-201554"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2024.109715"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2108502"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000001437"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-019-02680-z"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23094547"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.5146\/tjpath.2020.01508"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12301-024-00459-6"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-244192"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/life13091916"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0000000000004507"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.85639"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.72828"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsi.2012.08.003"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2010.05.007"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-002-0468-3"},{"key":"e_1_2_11_19_2","first-page":"1201","article-title":"Giant Condyloma Acuminatum or Buschke-Lowenstein Tumor: Review of the Literature and Report of Three Cases Treated by CO2 Laser Surgery. A Long-Term Follow-Up","volume":"22","author":"Frega A.","year":"2002","journal-title":"Anticancer Research"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02052606"}],"container-title":["Case Reports in Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/cris\/4587993","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/cris\/4587993","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/cris\/4587993","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T10:58:17Z","timestamp":1792493897000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/cris\/4587993"}},"subtitle":[],"editor":[{"given":"Semonti","family":"Nandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/cris\/4587993"],"URL":"https:\/\/doi.org\/10.1155\/cris\/4587993","archive":["Portico"],"relation":{},"ISSN":["2090-6900","2090-6919"],"issn-type":[{"value":"2090-6900","type":"print"},{"value":"2090-6919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-04-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"4587993"}}