{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T15:11:31Z","timestamp":1784214691662,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"vor","delay-in-days":143,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Neurological Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>The appearance of eosinophils in the cerebrospinal fluid (CSF) is considered atypical in patients with myelin oligodendrocyte glycoprotein (MOG) antibody\u2013associated disease (MOGAD). In this article, we report the case of a 24\u2010year\u2010old male who received an influenza vaccine and subsequently presented with sensory disturbances in his limbs and trunk, accompanied by urinary retention. On spinal cord magnetic resonance imaging (MRI), T2\u2010weighted images showed intramedullary high\u2010intensity lesions. Meanwhile, brain MRI revealed no lesions. CSF testing showed pleocytosis (180\u2009cells\/\u03bcL), and eosinophils were present in approximately 6% of the CSF white blood cells. Additionally, MOG antibodies (MOG\u2010IgG) were present in the serum and CSF, leading to the diagnosis of MOG\u2010IgG\u2013associated myelitis induced by immunization following influenza vaccination. It is speculated that perivascular infiltration of eosinophils can occur within demyelinating lesions in patients with MOGAD, possibly due to elevated levels of eosinophil\u2010associated cytokines and chemokines in the central nervous system (CNS) lesions. However, it remains unclear whether immunological responses triggered by vaccination contribute to the secretion of these mediators in such lesions.<\/jats:p>","DOI":"10.1155\/crnm\/6886402","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T06:43:51Z","timestamp":1779691431000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Eosinophil Recruitment and Activity in CNS Lesions of MOG Antibody\u2013Associated Myelitis Following Influenza Vaccination: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0488-6264","authenticated-orcid":false,"given":"Hiroshi","family":"Adachi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misa","family":"Takashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naonobu","family":"Futamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,24]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2011.03.038"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2017.10.074"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1172\/jci67554"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2021.102940"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/1756286418762083"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-020-01824-2"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-020-01825-1"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2024.105526"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2018.10.003"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/nxi.0000000000001038"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1137998"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf151"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1116-7"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000148481.80152.bf"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awaa102"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-020-02132-y"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2018-317969"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/ms9.0000000000001656"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2018.03.011"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.05.106"}],"container-title":["Case Reports in Neurological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crnm\/6886402","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crnm\/6886402","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crnm\/6886402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T14:51:00Z","timestamp":1784213460000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crnm\/6886402"}},"subtitle":[],"editor":[{"given":"Semonti","family":"Nandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crnm\/6886402"],"URL":"https:\/\/doi.org\/10.1155\/crnm\/6886402","archive":["Portico"],"relation":{},"ISSN":["2090-6668","2090-6676"],"issn-type":[{"value":"2090-6668","type":"print"},{"value":"2090-6676","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6886402"}}