{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T22:42:18Z","timestamp":1773787338305,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":348,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100006108","name":"Kult\u00farna a Edukacn\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR","doi-asserted-by":"publisher","award":["024SPU-4\/2023 012SPU-4\/2023"],"award-info":[{"award-number":["024SPU-4\/2023 012SPU-4\/2023"]}],"id":[{"id":"10.13039\/501100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>M\u00fcllerian agenesis, also known as vaginal agenesis, M\u00fcllerian aplasia, or Mayer\u2013Rokitansky\u2013K\u00fcster\u2013Hauser (MRKH) syndrome, is a rare developmental disorder affecting one in 5000 female births, resulting from an error in M\u00fcllerian duct fusion during fetal development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report<\/jats:title>\n                    <jats:p>We present a clinical case of a 46\u2010year\u2010old female patient, virgo intacta, with M\u00fcllerian agenesis and a leiomyoma arising from remnant uterine buds. The patient presented with primary amenorrhoea, continuous lower abdominal pain, and abdominal distension. We describe the diagnostic process and treatment strategy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>MRKH syndrome is the leading cause of vaginal agenesis, often accompanied by uterine and cervical aplasia. It is categorized into Type 1, which involves symmetric underdevelopment of the M\u00fcllerian ducts, and Type 2, characterized by asymmetric malformations of the genital tract and other congenital anomalies. Leiomyomas arising from remnant uterine tissue in MRKH patients are extremely rare. Accurate diagnosis and a carefully planned treatment strategy are essential for managing patients with MRKH syndrome complicated by rare tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this case, total tumor extirpation with bilateral adnexectomy was the preferred treatment, based on the patient\u2032s clinical presentation and diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crog\/4292888","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T06:35:17Z","timestamp":1765866917000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case of M\u00fcllerian Agenesis With a Giant Tumor Arising From Uterine Remnants"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-0904-5007","authenticated-orcid":false,"given":"Natalia","family":"Milczarska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4097-3192","authenticated-orcid":false,"given":"J\u00e1n","family":"Varga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4494-4519","authenticated-orcid":false,"given":"Karolina","family":"Just","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0849-2623","authenticated-orcid":false,"given":"Alexander","family":"Ostr\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,15]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002458"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/03000605211066394"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.21275\/sr24703222648"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2024.109957"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.4314\/ejhs.v25i4.14"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-1208.170418"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2021.105711"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(77)90801-8"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.34673"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2009.02.002"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10397-012-0747-3"}],"container-title":["Case Reports in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crog\/4292888","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crog\/4292888","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crog\/4292888","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T19:03:07Z","timestamp":1773774187000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crog\/4292888"}},"subtitle":[],"editor":[{"given":"Manvinder","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crog\/4292888"],"URL":"https:\/\/doi.org\/10.1155\/crog\/4292888","archive":["Portico"],"relation":{},"ISSN":["2090-6684","2090-6692"],"issn-type":[{"value":"2090-6684","type":"print"},{"value":"2090-6692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-11-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"4292888"}}