{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T22:44:25Z","timestamp":1773787465385,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":321,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The symptom and treatment of pancreatic ductal adenocarcinoma (PDA) at an advanced stage significantly deteriorate patients\u2032 quality of life (QOL). Therefore, multidisciplinary long\u2010term and palliative care is needed to maintain patients\u2032 physical, social, and psychological well\u2010being and ultimately improve survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>An octogenarian residing in a care center, which can provide multidisciplinary long\u2010term care with nutritional, physical, and social support, as well as pain management through home medical services, was diagnosed with Stage IV PDA. She received multiple outpatient chemotherapy sessions and experienced cancer\u2010related pain and fatigue. However, participating in individual functional training and altruistic social activities at the day service center, which is a crucial component of Japan\u2032s long\u2010term care system, within the care center maintained her high level of QOL for 5 years and 5 months until she died peacefully at the care center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Multidisciplinary care with nutritional support, palliative care, exercise, and social support at the care center may have reduced the patient\u2032s psychological stress and maintained her physical and psychological well\u2010being and ultimately improved her QOL and survival. The multidisciplinary care center may be a candidate for a new model system of palliative and hospice care that did not only provide pain\/symptom control and terminal care but also maintained a high QOL of the patient.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crom\/1775859","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T12:03:37Z","timestamp":1763467417000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Maintenance of a High Quality of Life of a Pancreatic Cancer Patient in a Multidisciplinary Care Center: A Case Report"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4731-8118","authenticated-orcid":false,"given":"Takayoshi","family":"Ubuka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Hirose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Sugimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoichi","family":"Yamane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,18]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1200\/EDBK_438598"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12837"},{"key":"e_1_2_11_3_2","first-page":"41","article-title":"Support for Improving Well-Being at the End of Life Through Geriatric Care","volume":"10","author":"Maki Y.","year":"2023","journal-title":"Journal of Geriatric Care and Research"},{"key":"e_1_2_11_4_2","first-page":"47","article-title":"Ageing in Place and Social Participation in Japan","volume":"10","author":"Maki Y.","year":"2023","journal-title":"Journal of Geriatric Care and Research"},{"key":"e_1_2_11_5_2","first-page":"35","article-title":"Functional Improvement Support in Day Services in Japan","volume":"10","author":"Maki Y.","year":"2023","journal-title":"Journal of Geriatric Care and Research"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-020-01666-y"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1304369"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-017-2349-y"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12274"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2011.12.017"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2019.0471"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13970"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13796"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/gps.2181"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2007.12.002"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/1745691614568352"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S57338"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2015.04.006"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-019-0595-x"},{"key":"e_1_2_11_20_2","first-page":"1294","article-title":"Chronic Stress-Induced Immune Dysregulation in Cancer: Implications for Initiation, Progression, Metastasis, and Treatment","volume":"10","author":"Zhang L.","year":"2020","journal-title":"American Journal of Cancer Research"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1032294"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1976-1317(11)60001-7"}],"container-title":["Case Reports in Oncological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crom\/1775859","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crom\/1775859","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crom\/1775859","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T19:03:56Z","timestamp":1773774236000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crom\/1775859"}},"subtitle":[],"editor":[{"given":"Jose I.","family":"Mayordomo","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crom\/1775859"],"URL":"https:\/\/doi.org\/10.1155\/crom\/1775859","archive":["Portico"],"relation":{},"ISSN":["2090-6706","2090-6714"],"issn-type":[{"value":"2090-6706","type":"print"},{"value":"2090-6714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-08-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1775859"}}