{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T22:43:37Z","timestamp":1773787417846,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:00:00Z","timestamp":1755216000000},"content-version":"vor","delay-in-days":226,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    T\u2010large granular lymphocytic (T\u2010LGL) leukemia is a rare hematological malignancy characterized by clonal expansion of cytotoxic T\u2010cells resulting in cytopenias. The diagnostic criteria for T\u2010LGL leukemia necessitated a sustained peripheral blood elevation of LGLs exceeding 2 \u00d7 10\n                    <jats:sup>9<\/jats:sup>\n                    \/L for a minimum duration of 6 months, in the absence of an identifiable etiology. In most of the cases, it is associated with autoimmune disorders such as rheumatoid arthritis. As cytopenias, including neutropenia, can be an early manifestation of the disease, they may get confused with Felty\u2019s syndrome, resulting in delayed diagnosis and treatment. Hence, we are presenting a rare case of diagnosing T\u2010LGL leukemia in a patient with rheumatoid arthritis with neutropenia and low LGL level.\n                  <\/jats:p>","DOI":"10.1155\/crom\/5013991","type":"journal-article","created":{"date-parts":[[2025,8,16]],"date-time":"2025-08-16T05:49:47Z","timestamp":1755323387000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case of T\u2010Large Granular Lymphocytic (T\u2010LGL) Leukemia in a Patient With Rheumatoid Arthritis With Neutropenia and Low LGL Level"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2657-426X","authenticated-orcid":false,"given":"Muhammad","family":"Daniyal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anamm","family":"Polani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7933-5774","authenticated-orcid":false,"given":"Pavel","family":"Bleik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8431-8373","authenticated-orcid":false,"given":"Jeffrey","family":"Allerton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,15]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/bcj.2016.59"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2009.03.515"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2022.07.004"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.5045\/br.2023.2023037"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/2324709620941303"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00393-024-01611-x"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2011.107"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2006.01.003"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2013.359"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S115892"}],"container-title":["Case Reports in Oncological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crom\/5013991","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crom\/5013991","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crom\/5013991","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T19:04:12Z","timestamp":1773774252000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crom\/5013991"}},"subtitle":[],"editor":[{"given":"Jose I.","family":"Mayordomo","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crom\/5013991"],"URL":"https:\/\/doi.org\/10.1155\/crom\/5013991","archive":["Portico"],"relation":{},"ISSN":["2090-6706","2090-6714"],"issn-type":[{"value":"2090-6706","type":"print"},{"value":"2090-6714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-06-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5013991"}}