{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T12:47:31Z","timestamp":1776516451807,"version":"3.51.2"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T00:00:00Z","timestamp":1776470400000},"content-version":"vor","delay-in-days":107,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mucinous carcinoma of the breast (MCB) is a rare histological subtype accounting for approximately 2% of all breast cancers, and it is characterized by abundant extracellular mucin production, indolent clinical behavior, and a favorable prognosis compared with other invasive breast carcinomas. Early and accurate recognition is essential due to its distinct pathological and immunohistochemical features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 50\u2010year\u2010old woman with no significant medical or family history presented with a palpable mass in her right breast, so she underwent breast screening. The imaging revealed multiple irregular nodular lesions with clustered microcalcifications in the right breast (BI\u2010RADS 4C), so she underwent a right modified radical mastectomy with axillary dissection. However, histopathological examination confirmed a well\u2010differentiated pure mucinous carcinoma (&gt;\u200990% mucinous component, Nottingham Grade I) without lymphovascular invasion or nodal metastasis (0\/13). The tumor was ER\/PR\u2013positive, HER2\u2010negative, with a low Ki\u201067 index (3%), and was completely excised with negative margins.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Pure MCB exhibits favorable biological behavior and excellent outcomes, particularly when accurately diagnosed through histopathological and immunohistochemical evaluation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pure MCB is a rare, low\u2010grade tumor with distinct pathological features. Accurate diagnosis and complete surgical excision are essential for optimal management, as patients typically achieve excellent long\u2010term outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crom\/6760604","type":"journal-article","created":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T12:04:37Z","timestamp":1776513877000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pure Mucinous Breast Carcinoma: Integrating Molecular and Immunohistochemical Profiles for Accurate Diagnosis\u2014A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2086-8248","authenticated-orcid":false,"given":"Hozaifa","family":"Hendi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0385-7624","authenticated-orcid":false,"given":"Hasan","family":"Asjiee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6507-0054","authenticated-orcid":false,"given":"Hamza","family":"Hendi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7704-0308","authenticated-orcid":false,"given":"Batoul","family":"Obeid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6573-5265","authenticated-orcid":false,"given":"Ahmad","family":"Alhaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,18]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2023.108652"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.4048\/jbc.2011.14.4.308"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.17076"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.7180\/kmj.22.022"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12672-025-03146-2"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.783631"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.8560"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000000373"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.2763"},{"key":"e_1_2_11_10_2","first-page":"14","article-title":"Mucinous Breast Cancer: A Review Study of 5 Year Experience From a Hospital-Based Series of Cases","volume":"10","author":"Dumitru A.","year":"2015","journal-title":"Maedica"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2008.06.004"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2020.02.010"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-007-9809-z"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1080\/08998280.2013.11928989"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2022.02.011"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1258\/ar.2010.100239"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2019.11.002"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1148\/rg.230015"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0155132"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2010.133"}],"container-title":["Case Reports in Oncological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crom\/6760604","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crom\/6760604","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crom\/6760604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T12:04:44Z","timestamp":1776513884000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crom\/6760604"}},"subtitle":[],"editor":[{"given":"Harleen","family":"Khatra","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crom\/6760604"],"URL":"https:\/\/doi.org\/10.1155\/crom\/6760604","archive":["Portico"],"relation":{},"ISSN":["2090-6706","2090-6714"],"issn-type":[{"value":"2090-6706","type":"print"},{"value":"2090-6714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-01-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6760604"}}