{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T08:04:43Z","timestamp":1779523483562,"version":"3.53.1"},"reference-count":44,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T00:00:00Z","timestamp":1779494400000},"content-version":"vor","delay-in-days":142,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cutaneous metastasis of gastric cancer is a rare manifestation (2.6%) of advanced gastrointestinal cancers and occurs in less than 1% of upper GI tract malignancies. The nodular type is the most common type. Tissue diagnosis and anatomic localization of the primary tumor are best obtained by upper gastrointestinal endoscopy. However, when the patient presents with dermatological and scalp lesions, the procedure is to take a targeted biopsy of said lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Summary<\/jats:title>\n                    <jats:p>A 60\u2010year\u2010old female with advanced disease (Stage IV HER2\u2010positive gastric cancer) was diagnosed due to skin metastases: erythematous alopecic skin lesions on the central scalp, as well as a raised, erythematous, indurated, nontender, irregular 6 \u00d7 8\u2009cm lesion on the cervicodorsal region. Treatment with capecitabine\u2009+\u2009oxaliplatin\u2009+\u2009trastuzumab every 3 weeks was initiated. By the sixth cycle, the scalp lesion had resolved completely, and the cervical lesion had reduced to 3 \u00d7 4\u2009cm. After 1 year of treatment, the lesions continued to show a favorable response.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>To the best of our knowledge, this is the second reported case of cutaneous metastases from HER2\u2010positive gastric cancer. Fewer than 20 cases involving metastases to the scalp and neck region have been reported in the English\u2010language literature.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crom\/9995795","type":"journal-article","created":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T07:17:42Z","timestamp":1779520662000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Scalp and Neck Metastasis From HER2\u2010Positive Gastric Cancer: A Case Report and Literature Review"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6886-4345","authenticated-orcid":false,"given":"Ricardo","family":"Fern\u00e1ndez-Ferreira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1048-5682","authenticated-orcid":false,"given":"Jesus","family":"Monta\u00f1o-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael-Garza","family":"Cant\u00fa-Pedraza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Delgado-Gutierrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato-Adrian","family":"Flores-Vazquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauricio-Lohengrin","family":"Dur\u00e1n-Aceves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ver\u00f3nica","family":"Bautista-Pi\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa-Mar\u00eda","family":"Vicu\u00f1a-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda-del-Carmen","family":"Burguete-Bojalil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovana-Ivette","family":"De-Lucio-Chavero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,23]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21820"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.10.007"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2009.07102.x"},{"key":"e_1_2_13_4_2","first-page":"194","article-title":"Metastatic Gastric Adenocarcinoma Presenting as an Enlarging Plaque on the Scalp","volume":"76","author":"Lifshitz O. 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