{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:50:28Z","timestamp":1791359428108,"version":"4.3.1"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":279,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Postvitrectomy endophthalmitis is a rare but vision\u2010threatening complication, with reported incidence rates below 0.15%, and treatment guidelines remain limited. Evidence guiding the timing of repeat vitrectomy in this setting is sparse, and the approach to management is derived largely from postcataract endophthalmitis.\n                    <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    endophthalmitis is associated with characteristically poor visual outcomes, often including enucleation. A 58\u2010year\u2010old man with a history of insulin\u2010dependent diabetes and proliferative diabetic retinopathy presented with conjunctival injection, corneal edema, hypopyon, and vitritis 2 days after elective 25\u2010gauge pars plana vitrectomy for vitreous opacities. His visual acuity had dropped from a preoperative baseline of 20\/30 to hand motion. The patient was initially treated with vitreous tap and intravitreal injection of vancomycin and amikacin at initial presentation of endophthalmitis and admitted for hourly topical moxifloxacin and prednisolone acetate 1%. Re\u2010evaluation after 12\u2009h showed persistently decreased vision and inflammation, with B\u2010scan ultrasonography showing active vitritis without retinal detachment. He was taken for repeat vitrectomy with intravitreal antibiotic injection within 24\u2009h of presentation. Vitreous culture was positive for\n                    <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    , which was susceptible to the empiric aminoglycoside. The patient\u2032s vision improved to 20\/200 at 2 weeks, then to his baseline of 20\/30 by 1 year postoperatively, remaining stable through a 3\u2010year follow\u2010up period. Early repeat vitrectomy within 24\u2009h of endophthalmitis presentation and prompt intravitreal antibiotic therapy for patients with postvitrectomy gram\u2010negative endophthalmitis can be associated with favorable visual outcomes. Early patient presentation, concordant antibiotic treatment, and absence of severe complications, such as retinal detachment or occlusive vasculitis, may have contributed to excellent recovery to baseline vision.\n                  <\/jats:p>","DOI":"10.1155\/crop\/4008092","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:00:46Z","timestamp":1791356446000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Favorable Outcome With Early Vitrectomy for Pseudomonas Endophthalmitis Following Elective Pars Plana Vitrectomy for Disabling Vitreous Opacities"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6062-4894","authenticated-orcid":false,"given":"Roselind L.","family":"Ni","sequence":"first","affiliation":[{"name":"Retina Service of Wills Eye Hospital Mid Atlantic Retina Thomas Jefferson University  Philadelphia Pennsylvania USA  jefferson.edu"},{"name":"Sidney Kimmel Medical College Thomas Jefferson University  Philadelphia Pennsylvania USA  jefferson.edu"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1712-0513","authenticated-orcid":false,"given":"Evelyn G.","family":"Miller","sequence":"additional","affiliation":[{"name":"Sidney Kimmel Medical College Thomas Jefferson University  Philadelphia Pennsylvania USA  jefferson.edu"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0670-2510","authenticated-orcid":false,"given":"Jonathan","family":"Perez","sequence":"additional","affiliation":[{"name":"Sargent College of Health &amp; Rehabilitation Sciences Boston University  Boston Massachusetts USA  bu.edu"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0179-1006","authenticated-orcid":false,"given":"Allen","family":"Chiang","sequence":"additional","affiliation":[{"name":"Retina Service of Wills Eye Hospital Mid Atlantic Retina Thomas Jefferson University  Philadelphia Pennsylvania USA  jefferson.edu"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Klufas","sequence":"additional","affiliation":[{"name":"Retina Service of Wills Eye Hospital Mid Atlantic Retina Thomas Jefferson University  Philadelphia Pennsylvania USA  jefferson.edu"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,7]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S71293"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2018.02.003"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000469"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e318203c183"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2010.06.002"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.01.045"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2024.102017"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3181fbce5c"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(03)00572-4"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/1265556"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1995.01100120009001"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2020-316846"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.15207"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S302757"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crop\/4008092","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crop\/4008092","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crop\/4008092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:00:47Z","timestamp":1791356447000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crop\/4008092"}},"subtitle":[],"editor":[{"given":"Semonti","family":"Nandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crop\/4008092"],"URL":"https:\/\/doi.org\/10.1155\/crop\/4008092","archive":["Portico"],"relation":{},"ISSN":["2090-6722","2090-6730"],"issn-type":[{"value":"2090-6722","type":"print"},{"value":"2090-6730","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-02-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"4008092"}}