{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T22:36:43Z","timestamp":1773787003961,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":43,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005888","name":"Uniwersytet Medyczny w Lodzi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005888","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>An 18\u2010year\u2010old male presented with bilateral vision loss, worsening over 10 days in the left eye and rapidly in the right eye following a suspected viral respiratory infection. On admission, his best corrected visual acuity (BCVA) was 0.9 in the right eye and 0.025 in the left. No inflammation was found in the anterior segment or vitreous body, but both eyes showed multiple yellow\u2013white, plaque\u2010like lesions in the retina and choroid, with foveal involvement in the left eye. Diagnostic tests revealed choriocapillaris flow deficits (optical coherence tomography angiography (OCTA)), hyperreflective changes in the outer retina and choroidal thickening (optical coherence tomography (OCT)), hypofluorescence and patchy hyperfluorescence (fluorescein angiography (FA)), hypoautofluorescence with peripheral hyperautofluorescence (fundus autofluorescence (FAF)), reduced a\u2010 and b\u2010wave amplitudes (electroretinogram (ERG)), and scotomas with decreased retinal sensitivity (visual field (VF)). The presence of HLA\u2010B15 and HLA\u2010B35 antigens was confirmed. Treatment with oral methylprednisolone and intravenous acyclovir led to significant improvement within 1 day. BCVA improved to 0.9 in the right eye and 0.25 in the left, with further improvement to 0.9 and 0.5 9\u2009days after discharge. Full visual recovery was achieved within 5 weeks. This case underscores the diagnostic value of OCTA and suggests a potential genetic predisposition linked to HLA\u2010B15 and HLA\u2010B35. It also highlights the effectiveness of methylprednisolone and acyclovir in APMPPE following a viral infection.<\/jats:p>","DOI":"10.1155\/crop\/9924678","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T23:19:26Z","timestamp":1739488766000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multimodal Imaging of a Case of Monitoring of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE): Long\u2010Term Follow\u2010Up"],"prefix":"10.1155","volume":"2025","author":[{"given":"Monika","family":"Sarna","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0327-5080","authenticated-orcid":false,"given":"Michal","family":"Wilczynski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4950-6390","authenticated-orcid":false,"given":"Arleta","family":"Waszczykowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1968.00980050179005"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajoc.2022.101790"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12348-023-00382-x"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000001900"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.79.4.384"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12348-021-00263-1"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2017.180"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/7049168"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-018-0744-z"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(01)00565-6"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1990.01070070084040"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)70234-X"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/5032881"},{"key":"e_1_2_10_14_2","first-page":"948","article-title":"HLA-B35 association with nephritis in Henoch-Sch\u00f6nlein purpura","volume":"29","author":"Amoli M. M.","year":"2002","journal-title":"The Journal of Rheumatology"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2020-001250"},{"key":"e_1_2_10_16_2","volume-title":"Retinal physiology and psychophysical response. Basic and Clinical Science Course, Section 12, Retina and Vitreous","author":"Rejdak R.","year":"2020"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58081070"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.901744"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0b013e3181aff47e"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crop\/9924678","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crop\/9924678","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crop\/9924678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T18:59:14Z","timestamp":1773773954000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crop\/9924678"}},"subtitle":[],"editor":[{"given":"Stephen G.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crop\/9924678"],"URL":"https:\/\/doi.org\/10.1155\/crop\/9924678","archive":["Portico"],"relation":{},"ISSN":["2090-6722","2090-6730"],"issn-type":[{"value":"2090-6722","type":"print"},{"value":"2090-6730","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9924678"}}