{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:50:59Z","timestamp":1787017859545,"version":"build-2736575974"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":193,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Otolaryngology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>While nasal and palatal necrosis secondary to intranasal cocaine use is well documented in the literature, similar presentations linked to heroin abuse are rarely described. To the best of our knowledge, laryngeal involvement has not previously been reported. We present the case of a 48\u2010year\u2010old man with a 25\u2010year history of smoking heroin, who presented with necrotic debris on the vocal cords and in the subglottic region. Debridement was performed, after which the symptoms subjectively improved. After one year, a subglottic adenocarcinoma was diagnosed. Substance abuse, including smoking heroin, should be considered in the differential diagnosis when necrotic laryngeal tissue is observed during laryngoscopic evaluation of patients with dysphonia and dyspnea. Biopsy and debridement are crucial for both diagnosis and symptom management. Long\u2010term follow\u2010up is essential, especially in patients with ongoing substance abuse, as malignancy can develop over time.<\/jats:p>","DOI":"10.1155\/crot\/5559965","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T10:35:46Z","timestamp":1783938946000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Laryngeal and Subglottic Necrosis Following Long\u2010Term Heroin 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