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Transcatheter aortic valve replacement (TAVR) for QAV remains uncertain.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    We retrospectively reviewed prospectively collected data from patients with QAV undergoing TAVR in our center and conducted a systematic literature review for further investigation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Five patients with QAV were treated with TAVR between April 2016 and December 2023. The median age was 67\u2009years (range: 59\u201386), and the median Society of Thoracic Surgeons score (STS\u2010score) was 3.750% (range: 0.916%\u201311.823%). Procedural success was achieved in all cases. The median follow\u2010up period was 3\u2009years (from 30\u2009days to 7\u2009years). Four of the patients exhibited no serious complications, while one experienced delayed coronary obstruction. Our systematic review included 31 cases from 21 publications and our center. The median age of patients was 79\u2009years (range: 57\u201390), including 18 males. The median STS score was 7.835%. Severe AS was present in 64.5% of the patients and severe AR in 41.9%. The most common QAV subtype was type B (48.4%). Technical success was achieved in 100% of the cases, with two cases reporting coronary obstruction and one required a permanent pacemaker implantation. During a median follow\u2010up period of 1\u2009year (from 30\u2009days to 7\u2009years), one case experienced serious complications of delayed coronary obstruction.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    The TAVR may be an alternative treatment for patients with QAV, preliminarily demonstrating feasible early and long\u2010term results from current experience. However, extra precautions regarding coronary artery obstruction complications are necessary due to the rarity and anatomical complexity of QAV.\n                  <\/jats:p>","DOI":"10.1155\/crp\/7815279","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T04:34:51Z","timestamp":1738730091000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transcatheter Aortic Valve Replacement in Patients With Quadricuspid Aortic Valve: A Case Series and Systematic Review"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6958-4640","authenticated-orcid":false,"given":"Wenjing","family":"Sheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7815-9490","authenticated-orcid":false,"given":"Dao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7782-891X","authenticated-orcid":false,"given":"Hanyi","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongrong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ailifeire","family":"Aihemaiti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1556-9198","authenticated-orcid":false,"given":"Xianbao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"e_1_2_16_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.017743"},{"key":"e_1_2_16_2_2","first-page":"454","article-title":"Quadricuspid Aortic Valve: A Comprehensive Review","volume":"31","author":"Yuan S.-M.","year":"2016","journal-title":"Brazilian Journal of Cardiovascular Surgery"},{"key":"e_1_2_16_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000932"},{"key":"e_1_2_16_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.09.039"},{"key":"e_1_2_16_5_2","first-page":"1","article-title":"Transcatheter Aortic Valve Replacement in Low-Risk Patients With Bicuspid Aortic Valve Stenosis","volume":"6","author":"Forrest J. 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