{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T22:44:31Z","timestamp":1773787471576,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":231,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Up to one\u2010third of germ cell tumors are extragonadal neoplasms, with yolk sac tumors (YSTs) being the most common malignant histology. This report describes the successful multimodal management of a primary YST of the stomach in a 2\u2010year\u2010old boy. The child presented with melena, and further evaluation revealed a mass lesion in the cardia of the stomach. A biopsy established a diagnosis of a YST, which correlated with an elevated serum alpha\u2010fetoprotein level. The child received three cycles of chemotherapy consisting of cisplatin, etoposide, and bleomycin (PEB), followed by surgical resection in the form of proximal gastrectomy. After an uneventful recovery from surgery, he received an additional three cycles of PEB and has remained disease\u2010free for 7\u2009years. This case highlights the potential for the occurrence of a relatively rare childhood tumor at an unusual site, which can pose diagnostic challenges. However, careful evaluation and meticulous management can lead to favorable outcomes.<\/jats:p>","DOI":"10.1155\/crpe\/1148505","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T05:04:48Z","timestamp":1755752688000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Primary Yolk Sac Tumor of the Stomach in a 2\u2010Year\u2010Old Boy: Case Report on a Rare Site for Extragonadal Malignant Germ Cell Tumor"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1521-1145","authenticated-orcid":false,"given":"Saiesh V.","family":"Reddy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subhash","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2649-9572","authenticated-orcid":false,"given":"Samreen S.","family":"Qureshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6770-5887","authenticated-orcid":false,"given":"Sajid S.","family":"Qureshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2011.10.005"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2195"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2014.417"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.4103\/ajps.ajps_105_22"},{"key":"e_1_2_10_5_2","first-page":"354","article-title":"Endodermal Sinus Tumour of stomach-A Case Report","volume":"50","author":"Baruah R.","year":"2007","journal-title":"Indian Journal of Pathology & Microbiology"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.4103\/jiaps.jiaps_17_18"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.33883\/jms.v22i2.396"}],"container-title":["Case Reports in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crpe\/1148505","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crpe\/1148505","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crpe\/1148505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T19:06:31Z","timestamp":1773774391000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crpe\/1148505"}},"subtitle":[],"editor":[{"given":"Anselm Chi-Wai","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crpe\/1148505"],"URL":"https:\/\/doi.org\/10.1155\/crpe\/1148505","archive":["Portico"],"relation":{},"ISSN":["2090-6803","2090-6811"],"issn-type":[{"value":"2090-6803","type":"print"},{"value":"2090-6811","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-03-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1148505"}}