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We present a newborn female patient suspected antenatally of having TSC based on fetal echocardiography, which suggested cardiac rhabdomyomas; these findings were confirmed postnatally. The patient was managed with regular multidisciplinary follow\u2010up and treated according to her presenting manifestations, including neonatal cardiac arrhythmias. This case highlights the importance of early genetic confirmation and proactive management of neonatal complications.<\/jats:p>","DOI":"10.1155\/crpe\/1952300","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T10:38:03Z","timestamp":1781865483000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prenatal Detection and Neonatal Management of Tuberous Sclerosis Complex Compounded by Symptomatic Cardiac Arrhythmia"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6597-9857","authenticated-orcid":false,"given":"Raja Imad Abu","family":"Iram","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman Hussein","family":"Karaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisham","family":"Dweik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5977-7227","authenticated-orcid":false,"given":"Mohammad I.","family":"Smerat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2261-14-66"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.3906\/sag-2002-133"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-017-2591-6"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(22)00213-7"},{"key":"e_1_2_8_5_2","volume-title":"Tuberous Sclerosis. 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