{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T06:15:02Z","timestamp":1788243302836,"version":"build-2803163510"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":242,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Ketamine misuse is an increasing public health concern among adolescents in the United Kingdom, with initiation reported as early as 14\u2009years of age and a rapidly rising demand for drug and alcohol support services. Chronic ketamine misuse is associated with significant urological sequelae, including ketamine\u2010induced uropathy, a condition increasingly encountered within paediatric and adolescent populations. Despite this trend, there remains a lack of unified paediatric\u2010specific management guidelines. We present the case of a 15\u2010year\u2010old boy who was referred urgently with abdominal pain and haematuria. Imaging revealed a thick\u2010walled, irregular bladder with vascular soft tissue plaques, alongside a significantly raised albumin\u2013creatinine ratio. Further assessment identified a history of heavy recreational ketamine use (up to 2\u2009g\/day) commencing at age 14. Following engagement with community drug and alcohol support services, the patient significantly reduced ketamine use, with subsequent improvement in symptoms, highlighting the potential reversibility of disease with early intervention and abstinence. This case underscores the emerging burden of ketamine\u2010induced uropathy in paediatric urology and the need for a structured, age\u2010appropriate management approach. Drawing on existing adult consensus guidance, we propose a tailored paediatric framework incorporating early noninvasive investigations, stepwise escalation of treatment, multidisciplinary involvement and close collaboration with youth\u2010focused substance misuse services. Increased reporting and research into paediatric ketamine uropathy are essential to clarify disease trajectory, inform clinical guidelines and support public health strategies aimed at reducing long\u2010term urological morbidity in young people.<\/jats:p>","DOI":"10.1155\/crpe\/2254453","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T05:34:36Z","timestamp":1788240876000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Paediatric Ketamine Bladder Case Report: A Burgeoning Problem in the Paediatric Population"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9291-9406","authenticated-orcid":false,"given":"Shreya","family":"Kulkarni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjun","family":"Visa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marita","family":"Isaac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6110-6693","authenticated-orcid":false,"given":"Joanne","family":"Parr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte Dunford","family":"E.","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravindar","family":"Anbarasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azad","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1612-5401","authenticated-orcid":false,"given":"Milind","family":"Kulkarni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"e_1_2_9_1_2","unstructured":"European Union Drug Agency EUDA Ketamine in Europe EMPACT Situation Report 2026 https:\/\/www.euda.europa.eu\/publications\/joint-publications\/ketamine-europe_en."},{"key":"e_1_2_9_2_2","volume-title":"Greater Manchester: Testing and Research on Emergent and New Drugs (GM TRENDS)","author":"Ralphs R.","year":"2024"},{"key":"e_1_2_9_3_2","volume-title":"Generation K: The Disturbing Rise of Ketamine Abuse Among Young People","author":"Deith J.","year":"2025"},{"key":"e_1_2_9_4_2","unstructured":"GOV.UK Children and Young People\u2019s Substance Misuse Treatment Statistics 2023 to 2024: Report 2026 https:\/\/www.gov.uk\/government\/statistics\/substance-misuse-treatment-for-young-people-2023-to-2024\/children-and-young-peoples-substance-misuse-treatment-statistics-2023-to-2024-report."},{"key":"e_1_2_9_5_2","volume-title":"Handbook of Substance Misuse and Addictions","author":"Castellani 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