{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:07:48Z","timestamp":1790856468948,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"vor","delay-in-days":273,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Neonatal sepsis caused by\n                      <jats:italic>Salmonella enterica<\/jats:italic>\n                      serovar Paratyphi A is rare and may present with nonspecific clinical features. Multidrug\u2010resistant strains pose substantial diagnostic and therapeutic challenges, particularly in resource\u2010limited settings.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>\n                      We report a preterm neonate born at 33\u2009weeks of gestation with a birth weight of 1800\u2009g who initially presented with respiratory distress and was managed as transient tachypnea of the newborn. The infant subsequently developed persistent fever, feeding intolerance, abdominal distension, leukopenia, severe thrombocytopenia, and elevated inflammatory markers despite initially negative blood cultures. A blood culture obtained on Day 20 of life grew multidrug\u2010resistant\n                      <jats:italic>S. Paratyphi A<\/jats:italic>\n                      , resistant to ceftriaxone, ciprofloxacin, pefloxacin, and trimethoprim\u2013sulfamethoxazole, with intermediate susceptibility to amikacin. The infant required blood\u2013product support and prolonged antimicrobial therapy. A 21\u2010day course of empiric cefoperazone\/sulbactam plus levofloxacin was administered with close monitoring and was temporally associated with clinical improvement and microbiological clearance. Blood cultures obtained on Days 45 and 50 were negative. No maternal or apparent healthcare\u2010associated source was identified.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Persistent multidrug\u2010resistant\n                      <jats:italic>S. Paratyphi A<\/jats:italic>\n                      bacteremia should be considered in neonates with refractory sepsis despite initially negative blood cultures. Repeated cultures, reassessment of antimicrobial susceptibility, and cautious individualized treatment are essential when laboratory capacity and therapeutic options are limited. The effectiveness of empiric salvage therapy cannot be established without direct susceptibility data and stronger supporting evidence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crpe\/2293042","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:31:12Z","timestamp":1790854272000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Persistent Multidrug\u2010Resistant\n                    <i>Salmonella enterica<\/i>\n                    Serovar Paratyphi A Bacteremia in a Preterm Neonate: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8516-4238","authenticated-orcid":false,"given":"Khat","family":"Sophea","sequence":"first","affiliation":[{"name":"Department of Neonatal Intensive Care Unit National Pediatric Hospital  Phnom Penh Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7872-0876","authenticated-orcid":false,"given":"Srey","family":"Viso","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory National Pediatric Hospital  Phnom Penh Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6954-0492","authenticated-orcid":false,"given":"Chean","family":"Soph\u00e2l","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Immunology National Pediatric Hospital  Phnom Penh Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"e_1_2_15_1_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00002-15"},{"key":"e_1_2_15_2_2","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.557"},{"key":"e_1_2_15_3_2","volume-title":"Performance Standards for Antimicrobial 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