{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T22:44:13Z","timestamp":1773787453699,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":243,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>We describe the clinical presentation and evaluation of an 11\u2010year\u2010old girl with no reported past medical history, seen by her primary care physician for intermittent knee pain. Outpatient X\u2010rays revealed findings concerning for rickets, prompting further evaluation with blood work. The patient was urgently referred to the emergency department due to abnormal laboratory results and was subsequently found to be in end\u2010stage kidney disease with severe anemia, metabolic acidosis, and significant electrolyte abnormalities. Despite these abnormalities, she was hemodynamically stable with appropriate mentation, and her physical exam was only pertinent for left knee pain. Nephrology was consulted, and she was admitted to the pediatric intensive care unit (PICU) for electrolyte repletion and emergent hemodialysis. This case demonstrates an atypically benign presentation of end\u2010stage kidney disease secondary to bilateral kidney dysplasia. It emphasizes the challenges of recognizing children with previously undetected congenital kidney disease and underscores the need for early detection in high\u2010risk populations, including those affected by social determinants of health.<\/jats:p>","DOI":"10.1155\/crpe\/8856638","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T11:18:21Z","timestamp":1756725501000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["From Intermittent Knee Pain to End\u2010Stage Kidney Disease: An Atypical Presentation of Bilateral Kidney Dysplasia in an 11\u2010Year\u2010Old Girl"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0973-6252","authenticated-orcid":false,"given":"Kristie","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9315-7028","authenticated-orcid":false,"given":"Carlos","family":"Araya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9728-086X","authenticated-orcid":false,"given":"Ryan","family":"Brogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,1]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2021.665661"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2023-062717"},{"key":"e_1_2_8_3_2","article-title":"Safe Motherhood","volume":"87","author":"Trevelyan J.","year":"1991","journal-title":"Nursing Times"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2011.03.003"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfac207"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnma.2022.05.002"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-021-05145-1"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0244709"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0000282021"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2022.12.014"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/biology12111395"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.128.2.295"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.3.e249"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2005.00455.x"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2020.10.021"}],"container-title":["Case Reports in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crpe\/8856638","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crpe\/8856638","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crpe\/8856638","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T19:05:33Z","timestamp":1773774333000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crpe\/8856638"}},"subtitle":[],"editor":[{"given":"Nikhat","family":"Kaura","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crpe\/8856638"],"URL":"https:\/\/doi.org\/10.1155\/crpe\/8856638","archive":["Portico"],"relation":{},"ISSN":["2090-6803","2090-6811"],"issn-type":[{"value":"2090-6803","type":"print"},{"value":"2090-6811","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-01-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8856638"}}