{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T11:08:16Z","timestamp":1789124896362,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":253,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Psychiatry"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>This case report describes a male patient in his 30s diagnosed with autism spectrum disorder (ASD), childhood\u2010onset temporal lobe epilepsy paired with nonepileptic seizures (NES), and treatment\u2010resistant schizophrenia (TRS). The patient was diagnosed with temporal lobe epilepsy in childhood and demonstrated features of ASD during adolescence. His psychiatric symptoms emerged during adolescence, including paranoid delusions, auditory and visual hallucinations, and pseudo\u2010seizures precipitated by psychosocial stressors. He has remained institutionalized in psychiatric care for over two decades due to severe impairments in reality testing and persistent, complex delusions, which are strongly influenced by ASD\u2010related hyperfixations on fictional characters. His symptoms include attributing personal experiences to fictional characters and engaging in media\u2010influenced spiritual battles. Treatment with clozapine has provided partial control of his psychotic symptoms, while sodium valproate has effectively managed his epilepsy. This case highlights the clinical intricacies associated with the coexistence of ASD, epilepsy, and TRS, underscoring the need for patient\u2010specific, multidisciplinary approaches to diagnosis and long\u2010term management.<\/jats:p>","DOI":"10.1155\/crps\/2386844","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T10:27:51Z","timestamp":1789122471000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Autism Spectrum Disorder, Temporal Lobe Epilepsy, and Treatment\u2010Resistant Schizophrenia With Media\u2010Themed Delusions and Impaired Insight: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6751-032X","authenticated-orcid":false,"given":"Myles","family":"Turkson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2554-7635","authenticated-orcid":false,"given":"Marian","family":"Taiwo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9300-5937","authenticated-orcid":false,"given":"Matthew","family":"Polden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1031-3708","authenticated-orcid":false,"given":"Jeremy","family":"Greening","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2009.06.004"},{"key":"e_1_2_10_2_2","first-page":"252","article-title":"Psychotic Disorders in Epilepsy: A Review","volume":"1","author":"Devinsky O.","year":"2000","journal-title":"Epilepsy and Behavior"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61539-1"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-011-0195-x"},{"key":"e_1_2_10_5_2","first-page":"34","article-title":"The Genetic Landscape of Intellectual Disability Arising From Epilepsy","volume":"50","author":"Gecz J.","year":"2009","journal-title":"Epilepsia"},{"key":"e_1_2_10_6_2","first-page":"614","article-title":"Prevalence of Non-Affective Psychoses in Individuals With Autism Spectrum Disorders: A Systematic Review","volume":"76","author":"De Giorgi R.","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"e_1_2_10_7_2","first-page":"361","article-title":"The Association Between Autism Spectrum Disorder and Psychotic Experiences in the ALSPAC Cohort","volume":"202","author":"Sullivan S. 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