{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T19:28:05Z","timestamp":1780514885988,"version":"3.54.1"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"vor","delay-in-days":198,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Psychiatry"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    Drug\u2010induced myoclonus is a rare adverse effect associated with several drug classes, including antipsychotics. This case report describes a patient who developed generalized myoclonic jerks while on long\u2010term risperidone therapy, in the context of concomitant sertraline use, without fulfilling clinical criteria for serotonin syndrome.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Case Presentation:<\/jats:bold>\n                    We present a 73\u2010year\u2010old male patient with a history of cerebrovascular disease and behavioral symptoms treated with sertraline and risperidone. The patient developed sudden, generalized myoclonic movements. Neurological examination and imaging studies excluded acute structural pathology and metabolic or infectious causes. Serotonin syndrome was ruled out based on clinical findings. The myoclonus resolved rapidly after discontinuation of risperidone, without any specific symptomatic treatment, suggesting a potential drug\u2010related mechanism.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    This case highlights the importance of recognizing antipsychotic\u2010related myoclonus as a potentially reversible condition. Clinicians should consider drug\u2010induced myoclonus in the differential diagnosis and pay special attention to the risks posed by polypharmacy involving psychotropic agents.\n                  <\/jats:p>","DOI":"10.1155\/crps\/7576076","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T08:51:16Z","timestamp":1752828676000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Generalized Myoclonus in an Elderly Patient on Risperidone: A Rare but Important Adverse Effect"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7274-025X","authenticated-orcid":false,"given":"\u00d6zlem","family":"Totuk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4199-442X","authenticated-orcid":false,"given":"\u00d6zge","family":"G\u00f6n\u00fcl \u00d6ner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,18]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5359.44024"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-020-00922-6"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.4065\/74.6.565"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucli.2006.12.003"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.12205"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1C228"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000351671"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200418020-00003"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2022.108693"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001393"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)92042-3"}],"container-title":["Case Reports in Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crps\/7576076","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crps\/7576076","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crps\/7576076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T18:58:14Z","timestamp":1773773894000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crps\/7576076"}},"subtitle":[],"editor":[{"given":"Erik","family":"J\u00f6nsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crps\/7576076"],"URL":"https:\/\/doi.org\/10.1155\/crps\/7576076","archive":["Portico"],"relation":{},"ISSN":["2090-682X","2090-6838"],"issn-type":[{"value":"2090-682X","type":"print"},{"value":"2090-6838","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-04-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"7576076"}}