{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T22:28:42Z","timestamp":1773095322482,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":67,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pulmonology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Lymphomatoid granulomatosis (LYG) is a rare, Epstein\u2013Barr virus (EBV)\u2013associated lymphoproliferative disorder characterized by angiocentric and angiodestructive infiltrates that most commonly involve the lungs. We report a case of a 38\u2010year\u2010old female with a history of latent tuberculosis who presented with a 3\u2010day history of fever, productive cough, bilateral lower extremity edema, and painless lower extremity skin lesions. Initial imaging revealed bilateral pulmonary nodules, and an extensive infectious workup was unrevealing. To obtain diagnostic tissue from peripheral lesions, she underwent robotic\u2010assisted bronchoscopy with targeted transbronchial biopsy. Histopathologic analysis revealed angiocentric and angiodestructive infiltrates with EBV positivity in CD20\u2010positive B cells, consistent with Grade 3 LYG. She was treated with dose\u2010adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (DA\u2010EPOCH\u2010R) chemotherapy, with initial radiographic response. However, she later developed refractory LYG complicated by hemophagocytic lymphohistiocytosis (HLH) and died of progressive disease. Robotic\u2010assisted bronchoscopy enabled safe, targeted sampling of peripheral pulmonary nodules, avoiding more invasive surgical biopsy.<\/jats:p>","DOI":"10.1155\/crpu\/5840915","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T12:19:19Z","timestamp":1773058759000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Grade 3 Pulmonary Lymphomatoid Granulomatosis Diagnosed by Robotic\u2010Assisted Bronchoscopy: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6994-5606","authenticated-orcid":false,"given":"Matthew","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6355-229X","authenticated-orcid":false,"family":"Hussain Alkhafaji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6287-4569","authenticated-orcid":false,"given":"Miguel","family":"Cantu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9186-9187","authenticated-orcid":false,"given":"Kim","family":"Styrvoky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5071-6152","authenticated-orcid":false,"given":"Steven","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000328"},{"key":"e_1_2_11_2_2","doi-asserted-by":"crossref","DOI":"10.1186\/1756-8722-2-39","article-title":"K Kosuri, D Tamkus, MCW de, and HT Chang, Lymphomatoid Granulomatosis Masquerading as Interstitial Pneumonia in a 66-Year-Old Man: A Case Report and Review of Literature","volume":"2","author":"Makol A.","year":"2009","journal-title":"Journal of Hematology & Oncology"},{"key":"e_1_2_11_3_2","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1038\/modpathol.2011.149","article-title":"Current Histological Diagnosis of Lymphomatoid Granulomatosis","volume":"25","author":"Colby T. 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