{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T22:34:13Z","timestamp":1773786853600,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":317,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pulmonology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Systemic sclerosis (SSc) is a chronic connective tissue disease marked by immune system dysfunction, vascular damage, and progressing fibrosis involving the skin and various internal organs. Interstitial lung disease (ILD) represents one of the leading contributors to illness and death in patients with SSc. The management becomes more complex when complicated by opportunistic infections such as tuberculosis (TB), particularly in endemic regions. We present the case of a 45\u2010year\u2010old woman with complaints of generalized weakness for one\u2010week, intermittent fever, nausea and vomiting, and a weight loss of 5\u2009kg over the previous 2 months. Clinical examination showed skin thickening and sclerodactyly, which then diagnosed as SSc\u2010associated ILD (SSc\u2010ILD). High\u2010resolution computed tomography (HRCT) revealed reticular changes, ground\u2010glass opacities, and traction bronchiectasis, indicating a nonspecific interstitial pneumonia (NSIP) pattern. During the course of treatment, the patient developed a persistent productive cough, weight loss, and fever. Pulmonary TB was confirmed through acid\u2010fast bacilli smear and GeneXpert testing. Early recognition of dual pathology and coordinated care among rheumatology, pulmonology, and infectious disease teams are crucial for optimizing outcomes. This case underlines the need for vigilance in managing immunosuppressed patients in TB\u2010endemic settings and contributes to the literature on SSc\u2010ILD complicated by active TB.<\/jats:p>","DOI":"10.1155\/crpu\/8525357","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T06:48:46Z","timestamp":1763189326000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary Tuberculosis Complicating Interstitial Lung Disease in Systemic Sclerosis: A Case Report from a High TB Burden Country"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8349-8307","authenticated-orcid":false,"given":"Donny Ardika","family":"Novananda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1052-1961","authenticated-orcid":false,"given":"Garinda Alma","family":"Duta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5104-0817","authenticated-orcid":false,"given":"Resti Yudhawati","family":"Meliana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7857-6169","authenticated-orcid":false,"given":"Aris","family":"Sudarwoko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,14]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2022.2015327"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-022-02078-5"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-019-0980-7"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2020.20136"},{"key":"e_1_2_9_5_2","first-page":"445","article-title":"Recent Review: Tuberculosis in Indonesia: Burden and the Challenge of Under-Reporting","volume":"54","author":"Suryanti A. 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