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A retrospective analysis was conducted on data from 10 client\u2010owned dogs with mild to severe periodontitis and hyperlipidemia. Dental procedures such as periodontal probing and intraoral radiography, followed by scaling, curettage, and polishing, were performed. The teeth were extracted, and the gingival mucosa was sutured in five cases of severe periodontitis. Hematological and general biochemical tests and lipoprotein (i.e., chylomicrons, very low\u2010density lipoprotein (VLDL), low\u2010density lipoprotein, and high\u2010density lipoprotein) analyses were performed before and 4 weeks after periodontal treatments. Consequently, periodontal treatments significantly reduced the total triglyceride, VLDL\u2010triglyceride, and total cholesterol levels. 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