{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T08:10:02Z","timestamp":1793434202215,"version":"4.5.0"},"reference-count":52,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":334,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022ZD0209104"],"award-info":[{"award-number":["2022ZD0209104"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Depression and Anxiety"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although the link between psychopathological and behavioral issues and suicidality is well\u2010established, existing studies often focus on static timepoints, neglecting their dynamic nature and sex differences. This study investigates the trajectories of these symptoms from late childhood to early adolescence and their association with suicidality, while also examining variations by sex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included 7849 unrelated children from the Adolescent Brain Cognitive Development (ABCD) cohort, with assessments conducted over a 3\u2010year follow\u2010up period. Caregiver\u2010reported psychopathological and behavioral symptoms were assessed using the Child Behavior Checklist (CBCL) at baseline (ages 9\u201310) and during three subsequent annual follow\u2010ups. Youth\u2010reported suicidality was assessed at both baseline and the 3\u2010year follow\u2010up (ages 12\u201313) using the Kiddie Schedule for Affective Disorders and Schizophrenia (K\u2010SADS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Latent class growth analysis (LCGA) identified three trajectory groups for total problems, internalizing, and externalizing behaviors, and two trajectory groups for each dimension. All high symptom trajectory groups had a higher risk of suicidality compared to low symptom trajectory groups, with adjusted odds ratios (ORs) ranging from 1.35 to 3.15 (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009 &lt; 0.05). Persistent high anxious\/depressed symptoms showed the strongest association with suicidal ideation (SI; adjusted OR\u2009=\u20091.96,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009 &lt; 0.001), while persistent high attention problem was most strongly associated with suicide attempts (adjusted OR\u2009=\u20092.87,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009 &lt; 0.001). Persistently high anxious\/depressed symptoms most strongly predicted suicide\u2010related outcomes in girls (OR\u2009=\u20092.17, 95% confidence interval [CI]: 1.73\u20132.71), whereas high\u2010increasing withdrawn\/depressed symptoms showed the strongest association in boys (OR\u2009=\u20092.00, 95% CI: 1.53\u20132.60). Persistently high attention problems consistently and most strongly predicted suicide attempts in both sexes (boys: OR\u2009=\u20093.41, 95% CI: 1.52\u20137.65; girls: OR\u2009=\u20092.98, 95% CI: 1.72\u20135.14).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Trajectories of psychopathological and behavioral symptoms from late childhood to early adolescence are modestly associated with suicidality during this critical transition. Withdrawn\/depressed symptoms strongest predicted risk in boys, whereas anxious\/depressed symptoms were most salient in girls. Attention problems consistently predicted suicide attempts across both sexes. These findings emphasize the need for ongoing monitoring and early intervention for at\u2010risk youth to potentially reduce adolescent suicidality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/da\/9546609","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T10:39:42Z","timestamp":1764585582000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Sex Differences in Behavioral and Psychopathological Trajectories From Late Childhood to Early Adolescence: Implications for Suicidality Risk"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0178-9950","authenticated-orcid":false,"given":"Xiaoxia","family":"Duan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujie","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2187-2042","authenticated-orcid":false,"given":"Mingjing","family":"Situ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5773-0396","authenticated-orcid":false,"given":"Xinyi","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Jing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9488-8747","authenticated-orcid":false,"given":"Pei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaozhi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2220-6216","authenticated-orcid":false,"given":"Yi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,1]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30321-X"},{"key":"e_1_2_11_2_2","unstructured":"Health NIoM Centers for Disease Control and Prevention (CDC) WISQARS Leading Causes of Death Reports 2021."},{"key":"e_1_2_11_3_2","unstructured":"Prevention CfDCa Underlying Cause of Death 1999\u20132020 Request Deaths Occurring Through 2020 2025."},{"key":"e_1_2_11_4_2","volume-title":"Youth Risk Behavior Survey Data Summary and Trends Report: 2013\u20132023","author":"Prevention CfDCa","year":"2024"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.13106"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2021.08.020"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/sltb.12191"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature25770"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2022.101143"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2020.04.007"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2011.02446.x"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-021-01161-7"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2023.4961"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1037\/bul0000084"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-018-01270-9"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10964-011-9630-1"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-023-02187-8"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1037\/a0032247"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanwpc.2023.100979"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.3221"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)31612-X"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291712000438"},{"key":"e_1_2_11_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(21)00281-9"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.53166"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.1037\/hea0001353"},{"key":"e_1_2_11_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41386-020-0736-6"},{"key":"e_1_2_11_27_2","first-page":"1","volume-title":"Encyclopedia of Clinical Neuropsychology","author":"Achenbach T. 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