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Despite this, its treatment is variable often due to a lack of capacity within healthcare systems to support this vulnerable population. Community pharmacy staff could offer additional support. This systematic review identifies depression services led by community pharmacy staff, their service components, outcomes, and barriers\/facilitators to their implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Four bibliographic databases were searched (Medline, EMBASE, PsycINFO, and CINAHL) from 2000 onwards. Title\/abstract and full\u2010text screening was conducted. Data on the service components were mapped to the Template for Intervention Description and Replication (TIDieR). Clinical, humanistic, economic, and service outcomes were charted. Barriers and facilitators were mapped to the Consolidated Framework for Implementation Research (CFIR). Quality assessment was performed using the Quality Assessment with Diverse Studies (QuADS) tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty studies were included. Seventeen studies identified general attitudes regarding community pharmacy services for depression, which were generally supportive. The majority (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200933) explored an implemented depression service focusing on depression advice\/education (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200915), screening (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200912), medication adherence (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094), medication review (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091), and disease therapy management (DTM) (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091). Clinical outcomes were the most commonly reported types of outcomes, with varied results. Key facilitators were linked to the pharmacy \u2018inner setting\u2019, including accessibility of community pharmacies, the use of private consultation rooms, and skills\/training of staff. Barriers to service delivery related often to the external \u2018outer setting\u2019, especially societal stigma, low public awareness of pharmacy roles, funding constraints, and limited collaboration with other healthcare professionals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This international review identified a range of different services that community pharmacy staff can deliver to support people with depression, ranging from supporting diagnosis, health literacy, and management plans. The accessibility of community pharmacies for depression service delivery warrants further investigation. However, limited empirical evidence of clinical and economic outcomes and reported implementation barriers may complicate broader implementation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/da\/9977874","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:33:42Z","timestamp":1783694022000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Systematic Review of Community Pharmacy\u2010Led Depression Services: Service Components, Outcomes, and Implementation Barriers and Facilitators"],"prefix":"10.1155","volume":"2026","author":[{"given":"David","family":"Kernaghan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisham","family":"Alshammari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3207-8091","authenticated-orcid":false,"given":"Gazala","family":"Akram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Pratt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Maxwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret C.","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1422-9415","authenticated-orcid":false,"given":"Natalie","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,10]]},"reference":[{"key":"e_1_2_9_1_2","unstructured":"World Health Organisation Depression and Other Common Mental Disorders: Global Health Estimates 2017."},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291723002349"},{"key":"e_1_2_9_3_2","volume-title":"Common Mental Health Conditions","author":"Liubertiene G.","year":"2025"},{"key":"e_1_2_9_4_2","unstructured":"MIND Centre for Mental Health The Big Mental Health Report 2024 2024."},{"key":"e_1_2_9_5_2","unstructured":"The Scottish Government Scottish Health Survey\u2013Telephone Survey\u2013August\/September 2020 2020."},{"key":"e_1_2_9_6_2","unstructured":"The Scottish Government Scottish Health Survey 2013: Summary Report 2014."},{"key":"e_1_2_9_7_2","unstructured":"World Health Organization World Mental Health Report: Transforming Mental Health for All 2022."},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2025.1599602"},{"key":"e_1_2_9_9_2","unstructured":"Local Government Association Public Health England The Community Pharmacy Offer for Improving the Public\u2019s Health 2016."},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2024-095540"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/pubmed\/fdi032"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-005764"},{"key":"e_1_2_9_13_2","volume-title":"Mental Health: Deprivation","author":"Scottish Public Health Observatory","year":"2020"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0222132"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1211\/096176702776868398"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2019.05.024"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40814-022-00992-7"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2021.11.001"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/sltb.12697"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.22605\/RRH6158"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare13151786"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-009828"},{"key":"e_1_2_9_23_2","unstructured":"RobinsonJ. 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