{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T03:47:43Z","timestamp":1773200863736,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":67,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatology Research and Practice"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pruritus is a frequent and debilitating complication in hemodialysis patients. Its pathophysiology remains poorly understood. This study aimed to describe the factors associated with pruritus in three hemodialysis centers in 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This was a prospective, descriptive, and analytical cross\u2010sectional study. It included 245 patients aged 18\u2009years and older, undergoing hemodialysis for at least three months, hemodynamically stable, and who had provided informed consent. Pruritus intensity was assessed using the Itch\u2010Numeric Rating Scale (Itch\u2010NRS). Statistical analysis was performed using Stata 17, with a significance level set at\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence of pruritus among hemodialysis patients was 40.41%. The mean age of participants was 52.75\u2009years, with a sex ratio of 1.78. Pruritus was most often mild to moderate (90.91%), generalized (48.48%), or diffuse (51.52%) and had been present for at least 1\u2009year in 67.67% of cases. The most frequently associated dermatoses were xeroderma (88.88%), nail abnormalities (77.14%), and diffuse hyperpigmentation (27.27%).<\/jats:p>\n                    <jats:p>\n                      Univariate analysis identified protective factors such as vitamin D supplementation, absence of anuria, absence of diffuse skin hyperpigmentation, absence of alopecia, and absence of nail abnormalities (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.003\u20130.042; OR\u2009=\u20090.17\u20130.58). Multivariate analysis showed that prolonged duration of hemodialysis, the use of an arteriovenous fistula, severe xeroderma, and the presence of Beau\u2019s lines (\n                      <jats:italic>p<\/jats:italic>\n                      \u2264 0.039) increased the risk of pruritus in hemodialysis patients. Conversely, the use of oral antidiabetic agents was significantly associated with a reduced risk of pruritus (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.003; OR\u2009=\u20090.25).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pruritus is a common and chronic condition in hemodialysis patients, adversely affecting their quality of life. The main risk factors identified were severe xeroderma, prolonged duration of hemodialysis, use of an arteriovenous fistula, and the presence of Beau\u2019s lines, whereas the use of oral antidiabetic medications appeared to be protective. A better understanding of the pathophysiology of pruritus in hemodialysis patients could help improve its management and enhance patient comfort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/drp\/4482167","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:55:45Z","timestamp":1773125745000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pruritus in Hemodialysis Patients in a Sub\u2010Saharan African Country: Benin\u2014Associated Skin Conditions and Other Factors in 2023 in Three Hemodialysis Centers"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4971-6774","authenticated-orcid":false,"given":"D\u00e9gbo\u00e9","family":"B\u00e9r\u00e9nice","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tounouga","family":"Dahlia Noelle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gb\u00e9nou","family":"Fabrice Mahou\u00e9na","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lossou","family":"Eric","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazoum\u00e8","family":"Rodrigue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vigan","family":"Jacques","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atadokp\u00e8d\u00e9","family":"F\u00e9lix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2016.25.142.7193"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/9186309"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.5262\/tndt.2014.1003.06"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071404"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12862"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000010633"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12051108"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nephro.2021.07.002"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S310550"},{"key":"e_1_2_11_10_2","first-page":"268","article-title":"Skin Changes in Patients With Chronic Renal Failure","volume":"22","author":"Falodun O.","year":"2011","journal-title":"Saudi Journal of Kidney Diseases and Transplantation"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2016.24.110.8639"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-021-01877-8"},{"key":"e_1_2_11_13_2","first-page":"1","article-title":"Mesure De La X\u00e9rose Et De La Desquamation","volume":"1","author":"Pi\u00e9rard G.","year":"2000","journal-title":"EMC\u2013Cosm\u00e9tologie"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.2147\/ccid.s418776"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-024-03922-2"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.29271\/jcpsp.2023.04.406"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nephro.2013.10.008"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.4103\/2229-5178.105458"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.krcp.2016.02.002"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.5414\/cnp74s013"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(17)30057-8"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfab218"},{"key":"e_1_2_11_23_2","doi-asserted-by":"crossref","DOI":"10.4081\/dr.2019.8310","article-title":"Factors Associated With the Severity of Pruritus in Patients With Terminal Chronic Kidney Disease Undergoing Hemodialysis in Lima, Peru","volume":"12","author":"Kossuth-Cabrejos S.","year":"2020","journal-title":"Dermatology Reports"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.33590\/emj\/10312319"},{"key":"e_1_2_11_25_2","first-page":"473","article-title":"In\u00e9galit\u00e9 Homme-Femme Face Aux Maladies R\u00e9nales Chroniques: Mythe Ou R\u00e9alit\u00e9","volume":"551","author":"Mehier P.","year":"2017","journal-title":"Revue Medicale Suisse"},{"key":"e_1_2_11_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-020-01594-x"},{"key":"e_1_2_11_27_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2020.11.026"},{"key":"e_1_2_11_28_2","first-page":"127","article-title":"Hemodialysis-Related Pruritus. 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