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SD presents in 40%\u201350% of all patients diagnosed with AGA. Although these conditions are traditionally discussed separately, increasing evidence suggests that they may share overlapping pathogenic factors, including androgen\u2010driven sebum hypersecretion, imbalance of the scalp microecology, barrier dysfunction, and inflammatory signaling. We propose an integrated framework for understanding SD\u2013AGA coexistence, emphasizing the interplay among endocrine influences, sebum alterations, microbial imbalance, and inflammatory activation. Therefore, the management of patients with coexisting AGA and SD should move beyond single\u2010target approaches and emphasize the restoration of scalp homeostasis, control of inflammatory cascades, and integration of antiandrogen therapy through comprehensive, individualized treatment strategies. This review may offer a new perspective for the combined management of these dual scalp disorders.<\/jats:p>","DOI":"10.1155\/drp\/8851971","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T09:01:30Z","timestamp":1791536490000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Double Challenges for Scalp Health: A Review of the Pathogenesis and Treatment Strategies of Coexistence of Seborrheic Dermatitis and Androgenetic Alopecia"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4107-085X","authenticated-orcid":false,"given":"Mengyan","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Dermatology Hangzhou Third People\u2019s Hospital  Hangzhou Zhejiang China  hz3yy.com"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6535-4502","authenticated-orcid":false,"given":"Lifang","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hangzhou Third People\u2019s Hospital  Hangzhou Zhejiang China  hz3yy.com"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17826"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-017-1280-y"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.12.077"},{"key":"e_1_2_11_4_2","first-page":"s135","article-title":"New Insight Into the Pathophysiology of Hair Loss Trigger a Paradigm Shift in the Treatment Approach","volume":"16","author":"Sadick N. 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