{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T20:23:42Z","timestamp":1770063822544,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"vor","delay-in-days":32,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatology Research and Practice"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Fixed pigmented erythema (FPE) is a common toxidermia characterized by the appearance of one or more annular, erythematous and hyperpigmented spots, following the systemic administration of a drug. The main aim of this study was to describe the epidemiological and clinical aspects of fixed pigmented erythema at the Departmental University Hospital Center Borgou\/Alibori (DUHC\u2010B\/A) from 2009 to 2022.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a descriptive cross\u2010sectional study with retrospective data collection, based on the records of patients seen in the Dermatology\u2010Venerology Unit for FPE. Initially, all files bearing the diagnosis of toxidermia were identified; then, those with the diagnosis of FPE with usable data were retained. Data were entered using EpiData 3.1 and analyzed using EpiData Analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixty\u2010four patients were enrolled during the study period. The prevalence of FPE was 0.73%, with a male predominance. The most common drug identified was cotrimoxazole, followed by paracetamol and quinine. Over half of the patients (52.9%) were self\u2010medicating.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although FPE occurs rarely, it remains the most frequent toxidermia at the DUHC\u2010B\/A. It can be severe in its generalized bullous form. Avoiding the practice of self\u2010medication could help reduce its prevalence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/drp\/9911682","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T09:52:36Z","timestamp":1770025956000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epidemiological and Clinical Profile of Fixed Pigmented Erythema at the Departmental University Hospital Center Borgou\/Alibori (Benin)"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7664-6209","authenticated-orcid":false,"given":"Fabrice","family":"Akpadjan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3686-9015","authenticated-orcid":false,"given":"Laura","family":"Dotsop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3248-7662","authenticated-orcid":false,"given":"Nad\u00e8ge","family":"Agbessi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1557-5830","authenticated-orcid":false,"given":"Christiane","family":"Koudoukpo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,2]]},"reference":[{"key":"e_1_2_10_1_2","first-page":"20-9","volume-title":"Rooks Textbook of Dermatology","author":"Breathnach S. M.","year":"2004"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0190-9622(03)01588-3"},{"key":"e_1_2_10_3_2","volume-title":"Fixed Drug Eruptions","author":"Butler D. F."},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.02853.x"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2005.02323.x"},{"key":"e_1_2_10_6_2","article-title":"Fixed Drug Eruptions Caused by Dyes","volume":"38","author":"Klevansky H.","year":"1964","journal-title":"South African Medical Journal"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/aci.0b013e32832cda4c"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0190-9622(94)70007-9"},{"key":"e_1_2_10_9_2","first-page":"320","article-title":"Eryth\u00e8me Pigment\u00e9 Fixe \u00e0 Cotonou, B\u00e9nin, de 1998 \u00e0 2008","volume":"138","author":"Atadokp\u00e8d\u00e9 F.","year":"2011","journal-title":"Annales de Dermatologie et de Venereologie"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13149-012-0237-x"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.4103\/1595-9587.169692"},{"key":"e_1_2_10_12_2","first-page":"514","article-title":"Profil Des Toxidermies M\u00e9dicamenteuses: \u00c9tude Prospective De 118 Cas","volume":"91","author":"Chaabane H.","year":"2013","journal-title":"La Tunisie M\u00e9dicale"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2010.0980"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04422.x"},{"key":"e_1_2_10_15_2","first-page":"1","article-title":"Fixed Drug Eruption: A Disease Mediated by Self-Inflicted Antigen-Specific Immune Responses","volume":"45","author":"Shiohara T.","year":"2007","journal-title":"Journal of Dermatological Science"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1586\/eci.11.66"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.2217\/pgs.12.108"},{"key":"e_1_2_10_18_2","first-page":"4","article-title":"Genetic Markers and Danger Signals in Severe Cutaneous Adverse Reactions","volume":"65","author":"Chung W. H.","year":"2010","journal-title":"Allergy"},{"key":"e_1_2_10_19_2","first-page":"344","article-title":"Current Perspectives on Fixed Drug Eruption","volume":"54","author":"Lerch M.","year":"2018","journal-title":"Clinical Reviews in Allergy and Immunology"}],"container-title":["Dermatology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/drp\/9911682","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/drp\/9911682","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/drp\/9911682","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T09:52:38Z","timestamp":1770025958000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/drp\/9911682"}},"subtitle":[],"editor":[{"given":"Tulika","family":"Banerjee","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/drp\/9911682"],"URL":"https:\/\/doi.org\/10.1155\/drp\/9911682","archive":["Portico"],"relation":{},"ISSN":["1687-6105","1687-6113"],"issn-type":[{"value":"1687-6105","type":"print"},{"value":"1687-6113","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-02-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9911682"}}