{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T09:05:04Z","timestamp":1770282304881,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic and Therapeutic Endoscopy"],"published-print":{"date-parts":[[1999,1]]},"abstract":"<jats:p>Laser endoscopic surgery, especially the effectiveness of photodynamic therapy (PDT) using\nPhotofrin as a photosensitizer, has now achieved a status as effective treatment modality for\nlung cancer. Twenty\u2010six lung cancer patients received the preoperative PDT for the purpose of\neither reducing the extent of resection or increasing operability. Bronchoscopical PDT is\nperformed with topical anesthesia approximately 48 h after the intravenous injection of\n2.0 mg\/kg body weight of Photofrin. Operation was performed 2\u20139 weeks after initial PDT. The initial purpose of PDT, i.e. either to reduce the extent of resection or convert inoperable\ndisease to operable status, was achieved in 22 out of 26 patients treated. The survival rate of T3\n(main bronchus invasion) cases treated by surgery alone increased significantly from 50.9% to\n60.0% with the application of preoperative PDT. This remarkable result may imply that this\nnew option of PDT as preoperative laser irradiation may contribute to the management of\nadvanced lung malignancy.<\/jats:p>","DOI":"10.1155\/dte.5.155","type":"journal-article","created":{"date-parts":[[2007,8,30]],"date-time":"2007-08-30T12:42:21Z","timestamp":1188477741000},"page":"155-160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Lung Cancers Treated With Photodynamic Therapy and Surgery"],"prefix":"10.1155","volume":"5","author":[{"given":"Tetsuya","family":"Okunaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshimitsu","family":"Hiyoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kinya","family":"Furukawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaaki","family":"Tsuchida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitsuo","family":"Usuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Kumasaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junzou","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chimori","family":"Konaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harubumi","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1999,1]]},"container-title":["Diagnostic and Therapeutic Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/1999\/903242.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/DTE.5.155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T16:17:06Z","timestamp":1723133826000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/DTE.5.155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,1]]}},"alternative-id":["10.1155\/DTE.5.155"],"URL":"https:\/\/doi.org\/10.1155\/dte.5.155","archive":["Portico"],"relation":{},"ISSN":["1070-3608","1029-0516"],"issn-type":[{"value":"1070-3608","type":"print"},{"value":"1029-0516","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,1]]},"assertion":[{"value":"1999-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}