{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T10:32:45Z","timestamp":1774866765498,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic and Therapeutic Endoscopy"],"published-print":{"date-parts":[[1999,1]]},"abstract":"<jats:p>We have been performing PDT using Excimer Dye Laser (EDL) or YAG\u2010OPO laser, a type\nof low power laser, both of which have a considerably higher degree of tissue penetration even\nwhen compared to PDT using Argon Dye Laser (ADL).<\/jats:p><jats:p>PDT is a relatively simple procedure without any bleeding and does not require anesthesia\nsince it causes no pain. PDT is performed 48 h after intravenous injection of 1.5\u20132.0 mg\/kg\nof PHE (Photofrin<jats:sup>\u00ae<\/jats:sup>). Precise spot irradiation is possible using a colposcope with an optical laser path. We also use a cervical probe which enables photoirradiation of the entire cervical canal.<\/jats:p><jats:p>We have performed PDT on 131 cases (95 CIS, 31 dysplasia, 1 vulval dysplasia (VIN),\n3 squamous cell carcinoma, microinvasion, and 1 CIS + endocervical adenocarcinoma,\nmicroinvasion). Of these cases, 127 became CR (96.9%). The first CR case was 10 years ago\nand no recurrence has been observed yet.<\/jats:p><jats:p>PDT is extremely effective to preserve fertility. Except for sensitive reactions to sunlight,\nthere are no noticeable side effects or difficulties related to pregnancy or delivery. We expect\nthat in the near future PDT will be performed using diode lasers and without hospitalization\ndue to new photosensitizers which have shorter retention times.<\/jats:p>","DOI":"10.1155\/dte.5.183","type":"journal-article","created":{"date-parts":[[2007,8,30]],"date-time":"2007-08-30T12:42:21Z","timestamp":1188477741000},"page":"183-190","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Application of PDT for Uterine Cervical Cancer"],"prefix":"10.1155","volume":"5","author":[{"given":"T.","family":"Muroya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Kawasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Suehiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Kunugi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Umayahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Akiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Iwabuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Sakunaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Sugishita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Tenjin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1999,1]]},"container-title":["Diagnostic and Therapeutic Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/1999\/272470.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/DTE.5.183","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T16:17:03Z","timestamp":1723133823000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/DTE.5.183"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,1]]}},"alternative-id":["10.1155\/DTE.5.183"],"URL":"https:\/\/doi.org\/10.1155\/dte.5.183","archive":["Portico"],"relation":{},"ISSN":["1070-3608","1029-0516"],"issn-type":[{"value":"1070-3608","type":"print"},{"value":"1029-0516","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,1]]},"assertion":[{"value":"1999-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}