{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T04:22:48Z","timestamp":1724991768301},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic and Therapeutic Endoscopy"],"published-print":{"date-parts":[[1999,1]]},"abstract":"<jats:p><jats:italic>Aims and objectives<\/jats:italic> The present study was undertaken to compare the diagnostic yield\nof three available test procedures for detecting <jats:italic>Helicobacter pylori<\/jats:italic> (<jats:italic>H. pylori<\/jats:italic>) infection in endoscopic biopsies.<\/jats:p><jats:p><jats:italic>Methods H. pylori<\/jats:italic> infection was sought in 150 patients referred for upper gastrointestinal\n(GI) endoscopy. Multiple (about six) biopsy specimens were taken from pyloric\nantrum in each patient. Two biopsy specimens were subjected to one minute endoscopy\nroom test \u2013 OMERT (a modified form of urease test), two were sent for histopathological\nanalysis, where multiple sections were subjected to Giemsa staining and two were sent for\nmicrobiological evaluation after Gram\u2032s staining of heat fixed biopsy material.<\/jats:p><jats:p><jats:italic>Results H. pylori<\/jats:italic> positivity using histology, microbiology and OMERT was observed\nto be 33%, 30% and 27% respectively. However, overall 40% patients were infected when\nthe results from three test procedures were combined, as <jats:italic>H. pylori<\/jats:italic> positivity was repeated\nmore than once by these procedures separately. Histology was found to be superior to other\ntwo tests in our study, especially when multiple sections were examined, for the distribution\nof the organism was patchy. Amongst the infected, <jats:italic>H. pylori<\/jats:italic> was seen in only 30% of all\n3\u20138 sections cut from a biopsy, whereas in 70% it was noted in a single section only.<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic> The study revealed that histology has the highest detection rate and can be\nchosen as the \u201cgold standard\u201d amongst the three low cost test procedures available at present\nin our setup.<\/jats:p>","DOI":"10.1155\/dte.6.25","type":"journal-article","created":{"date-parts":[[2007,8,30]],"date-time":"2007-08-30T12:42:21Z","timestamp":1188477741000},"page":"25-29","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["<i>Helicobacter pylori<\/i> Infection in Endoscopic Biopsy Specimens of Gastric Antrum: Laboratory Diagnosis and Comparative Efficacy of Three Diagnostic Tests"],"prefix":"10.1155","volume":"6","author":[{"given":"G. M.","family":"Malik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mubarik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. A.","family":"Kadla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1999,6,17]]},"container-title":["Diagnostic and Therapeutic Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/1999\/109680.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/dte\/1999\/109680.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/DTE.6.25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T04:13:51Z","timestamp":1723090431000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/DTE.6.25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,1]]}},"alternative-id":["10.1155\/DTE.6.25"],"URL":"https:\/\/doi.org\/10.1155\/dte.6.25","archive":["Portico"],"relation":{},"ISSN":["1070-3608","1029-0516"],"issn-type":[{"type":"print","value":"1070-3608"},{"type":"electronic","value":"1029-0516"}],"subject":[],"published":{"date-parts":[[1999,1]]},"assertion":[{"value":"1999-02-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-06-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-06-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}