{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T05:05:36Z","timestamp":1769231136269,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic and Therapeutic Endoscopy"],"published-print":{"date-parts":[[1999,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic> This study aimed to find out prevalence of <jats:italic>Helicobacter pylori<\/jats:italic> (<jats:italic>H. pylori<\/jats:italic>) in peptic ulcer disease (PUD) which is highly endemic disease in Kashmir.<\/jats:p><jats:p><jats:italic>Method<\/jats:italic> This study consisted of 50 PUD patients and 30 asymptomatic volunteers.\nPeptic ulcer was diagnosed by endoscopic examination and <jats:italic>H. pylori<\/jats:italic> was detected by histology\n(using Giemsa stain), one minute endoscopy room test (OMERT) and modified\nGram\u2032s staining. Positive results from OMERT plus histology were considered as the\n\u201c<jats:italic>gold standard<\/jats:italic>\u201d for the presence of <jats:italic>H. pylori<\/jats:italic>.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic> Out of 50 patients, 46 had duodenal ulcer (DU), 2 had benign gastric ulcer\n(GU) and 2 had both DU and GU. The sensitivity and specificity of OMERT were 94%\nand 96.70%, histology 97.90% and 96.90% and Gram\u2032s staining 91.30% and 85.30%,\nrespectively, as compared to our gold standards. <jats:italic>H. pylori<\/jats:italic> was present in 76.09% of DU,\n50% of GU, whereas patients with duodenitis, channel ulcers, chronic active DU and those\nwith multiple ulcers were 100% <jats:italic>H. pylori<\/jats:italic> positive. <jats:italic>H. pylori<\/jats:italic> was present in 10 (33.33%) of healthy volunteers.<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic> A significant association between <jats:italic>H. pylori<\/jats:italic> infection and PUD was found in this study. However, there seem to be other causative factors as well which contribute\nfor this highly endemic disease.<\/jats:p>","DOI":"10.1155\/dte.6.31","type":"journal-article","created":{"date-parts":[[2007,8,30]],"date-time":"2007-08-30T12:42:21Z","timestamp":1188477741000},"page":"31-36","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prevalence of <i>Helicobacter pylori<\/i> Infection in Peptic Ulcer Patients of Highly Endemic Kashmir Valley"],"prefix":"10.1155","volume":"6","author":[{"given":"Gh. Jeelani","family":"Romshoo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. M.","family":"Malik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. A.","family":"Basu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Yousuf","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. R.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1999,6,21]]},"container-title":["Diagnostic and Therapeutic Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/1999\/430723.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/DTE.6.31","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T04:13:57Z","timestamp":1723090437000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/DTE.6.31"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,1]]}},"alternative-id":["10.1155\/DTE.6.31"],"URL":"https:\/\/doi.org\/10.1155\/dte.6.31","archive":["Portico"],"relation":{},"ISSN":["1070-3608","1029-0516"],"issn-type":[{"value":"1070-3608","type":"print"},{"value":"1029-0516","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,1]]},"assertion":[{"value":"1999-03-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-06-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-06-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}