{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:22:09Z","timestamp":1782886929821,"version":"3.54.5"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":180,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emergency Medicine International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Dyspnea is a common and complex symptom in patients presenting to the emergency department, with multiple possible underlying diseases and a high risk of tracheal intubation or even death as the condition progresses. Therefore, an easily accessible, quick, and convenient index is needed to predict patient prognosis at emergency. A single measurement of peripheral capillary oxygen saturation (SpO\n                      <jats:sub>2<\/jats:sub>\n                      ) or respiratory rate (RR) is not sufficiently accurate, while other related indices are relatively complex. This study investigated the predictive value of the SpO\n                      <jats:sub>2<\/jats:sub>\n                      \/RR ratio (SR) in patients with acute dyspnea without oxygen therapy presenting to the emergency department.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center retrospective analysis was conducted in the emergency department of Jiangsu Provincial Hospital of Traditional Chinese Medicine. Patients diagnosed with acute dyspnea without oxygen therapy who were presented to the emergency triage by the 120 ambulance were included. SR was calculated from the first vital signs obtained at the 120 ambulance real\u2010time transmission system for vehicles. Patients were divided into three groups based on terciles. Kaplan\u2013Meier analysis, Cox regression models, and restricted cubic splines (RCS) were used to examine the associations between SR and clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 1339 patients were included. The rates of 7\u2010day intubation and 28\u2010day mortality differed significantly across SR groups (22.77%, 15.28%, 15.25%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) and (24.55%, 15.06%, 11.88%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), respectively. Cox regression and Kaplan\u2013Meier analyses showed that lower SR was significantly associated with greater intubation and mortality risk (log\u2010rank\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Subgroup and sensitivity analyses supported these findings, with the effect more pronounced in patients with an RR of \u2265\u200930 breaths\/min. RCS nonlinear analysis revealed L\u2010shaped associations between SR and 7\u2010day intubation and 28\u2010day mortality, with inflection points identified at 4.85 and 3.53.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A lower SR was associated with increased 7\u2010day intubation and 28\u2010day mortality in emergency department patients with acute dyspnea without oxygen therapy. Inflection points of 4.85 and 3.53 suggest that SR may serve as a useful prognostic indicator for identifying high\u2010risk patients with acute dyspnea.<\/jats:p>\n                    <jats:p>Yuwei Tan and Sicheng Yuan contributed equally to this work and both as co\u2010first authors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/emmi\/1372222","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:01:07Z","timestamp":1782882067000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive Value of SpO2\/RR Ratio for Short\u2010Term Intubation and Mortality Risks in Pre\u2010ED Patients With Acute Dyspnea Without Oxygen Therapy: A Retrospective Cohort Study"],"prefix":"10.1155","volume":"2026","author":[{"given":"Yuwei","family":"Tan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3968-5401","authenticated-orcid":false,"given":"Sicheng","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panpan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqian","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8752-1188","authenticated-orcid":false,"given":"Li","family":"Dou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7403-581X","authenticated-orcid":false,"given":"Tao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2005.06.007"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-023-03322-8"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1817-7578"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.31729\/jnma.4582"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/MEJ.0b013e328351e609"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-024-04903-5"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13049-016-0273-9"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10877-023-00995-6"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00063-015-0061-8"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.4103\/njcp.njcp_2026_21"},{"key":"e_1_2_13_11_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-120485"},{"key":"e_1_2_13_12_2","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2023.32.13.620"},{"key":"e_1_2_13_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/eci.13875"},{"key":"e_1_2_13_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0265559"},{"key":"e_1_2_13_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2023.09.002"},{"key":"e_1_2_13_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2682-1"},{"key":"e_1_2_13_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0000000000000372"},{"key":"e_1_2_13_18_2","doi-asserted-by":"publisher","DOI":"10.2478\/jccm-2025-0024"},{"key":"e_1_2_13_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002514"},{"key":"e_1_2_13_20_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0617"},{"key":"e_1_2_13_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2016.01.003"},{"key":"e_1_2_13_22_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.15-0169"},{"key":"e_1_2_13_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-024-02771-9"},{"key":"e_1_2_13_24_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11020342"},{"key":"e_1_2_13_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-024-01902-8"},{"key":"e_1_2_13_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.medine.2025.502136"},{"key":"e_1_2_13_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2023.09.036"},{"key":"e_1_2_13_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(24)00118-8"},{"key":"e_1_2_13_29_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202203-0561LE"},{"key":"e_1_2_13_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2025.03.010"},{"key":"e_1_2_13_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/crj.70098"}],"container-title":["Emergency 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