{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:49:01Z","timestamp":1787017741535,"version":"build-2736575974"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":315,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Global Health, Epidemiology and Genomics"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transfusion\u2010related infections are a severe threat to the safety of transfusing blood products internationally. Advances in screening procedures have not, nevertheless, rendered blood transfusion a risk\u2010free procedure for transmitting infectious disease(s).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of this study was to determine donors\u2019 histories that could influence the possibility of transfusion\u2010related infections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a cross\u2010sectional study. Data for 108 donors were retrieved from donor medical records and donor screening forms. Variables were analyzed for their link with TRIs. The diagnosis of TRIs was established based on the results of a clinical examination and laboratory tests. Using descriptive statistics as well as chi\u2010square tests and logistic regression, data were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the total donor sample, 13.9% of donor blood units were found to be infected with TTI and were therefore not transfused to the patients; in these cases, 4.6% had hepatitis B infections, whereas 3.7% had HIV infections and 5.6% had malaria infections. Past donor experience and risky behavior, which include intravenous drug use and other risky sexual practices, show a significant association between the increased risk of TRIs (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05). The odds of transfusion\u2010transmitted infections among repeat donors as compared to first\u2010time donors were marginally high (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.04). These independent risk factors for transfusion\u2010related infections were hepatitis B and HIV.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The current study calls for a deliberate consideration of donor history, especially previous donation records, medical conditions, and high\u2010risk behaviors, in the prevention of transfusion\u2010related infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/ghe3\/8585241","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T10:48:03Z","timestamp":1762944483000},"source":"Crossref","is-referenced-by-count":7,"title":["Impact of Donor History on the Risk of Transfusion\u2010Related Infections"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6176-8935","authenticated-orcid":false,"given":"Collince Odiwuor","family":"Ogolla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benard","family":"Guya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apollo O.","family":"Maima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,12]]},"reference":[{"key":"e_1_2_14_1_2","volume-title":"Blood Safety and Availability","author":"World Health Organization","year":"2020"},{"key":"e_1_2_14_2_2","first-page":"195","article-title":"Evaluation of the Risk of Transfusion-Transmitted Infections in Blood Donors","volume":"58","author":"Youssouf M.","year":"2019","journal-title":"Transfusion and Apheresis Science"},{"key":"e_1_2_14_3_2","first-page":"12","article-title":"Window Period and Its Impact on Transfusion Safety: The Challenge of Early Detection in Blood Donations","volume":"91","author":"Chia Y.","year":"2017","journal-title":"Journal of Clinical Virology"},{"key":"e_1_2_14_4_2","first-page":"22","article-title":"The Role of High-Risk Behavior in Transfusion-Related Infections","volume":"34","author":"Stone G.","year":"2020","journal-title":"Transfusion Medicine Reviews"},{"key":"e_1_2_14_5_2","first-page":"250","article-title":"Safety of Blood Transfusions and the Role of Donor History","volume":"112","author":"Vamvakas E. C.","year":"2017","journal-title":"Vox Sanguinis"},{"key":"e_1_2_14_6_2","first-page":"324","article-title":"First-Time vs. Repeat Blood Donors: Are Repeat Donors at Higher Risk for Transfusion-Transmitted Infections?","volume":"26","author":"Kaur R.","year":"2016","journal-title":"Transfusion Medicine"},{"key":"e_1_2_14_7_2","first-page":"250","article-title":"Advances in Blood Screening: Nucleic Acid Testing and Its Role in Transfusion Safety","volume":"118","author":"Nascimento P.","year":"2020","journal-title":"Vox Sanguinis"},{"key":"e_1_2_14_8_2","article-title":"The Burden of Transfusion-Transmitted Malaria: A Review of Current Screening Practices in Malaria-Endemic Regions","volume":"17","author":"Lwilla F.","year":"2018","journal-title":"Malaria Journal"},{"key":"e_1_2_14_9_2","first-page":"981","article-title":"Limitations of Hepatitis C Screening Assays and the Need for More Sensitive Diagnostic Tests","volume":"54","author":"Salahuddin N.","year":"2016","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_14_10_2","first-page":"439","article-title":"Nucleic Acid Testing for Hepatitis C: Enhancing Blood Safety","volume":"3","author":"Chamberlain D.","year":"2016","journal-title":"Lancet Haematology"},{"key":"e_1_2_14_11_2","unstructured":"World Health Organization Blood Safety and Availability 2021 https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/blood-safety-and-availability."},{"key":"e_1_2_14_12_2","first-page":"129","article-title":"Prevention of Transfusion-Transmitted Infections in the Modern Blood Supply","volume":"58","author":"Baker J.","year":"2018","journal-title":"Transfusion and Apheresis Science"},{"key":"e_1_2_14_13_2","first-page":"257","article-title":"Safety of Blood Transfusions: Understanding the Risks","volume":"112","author":"Vamvakas E. C.","year":"2017","journal-title":"Vox Sanguinis"},{"key":"e_1_2_14_14_2","first-page":"1","article-title":"Bacterial Contamination of Blood Products and Its Impact on Transfusion Safety","volume":"104","author":"Bourgoin T.","year":"2013","journal-title":"Vox Sanguinis"},{"key":"e_1_2_14_15_2","first-page":"587","article-title":"Malaria Transmission Through Blood Transfusion in Sub-Saharan Africa: Challenges and Solutions","volume":"14","author":"White N. J.","year":"2014","journal-title":"The Lancet Infectious Diseases"},{"key":"e_1_2_14_16_2","first-page":"150","article-title":"Improving Malaria Screening in Blood Transfusions: A Global Perspective","volume":"26","author":"Krause J.","year":"2016","journal-title":"Transfusion Medicine"},{"key":"e_1_2_14_17_2","article-title":"Impact of Donor History on the Risk of Transfusion-Related Infections","author":"Ogolla C. O.","year":"2025","journal-title":"medRxiv"}],"container-title":["Global Health, Epidemiology and Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/ghe3\/8585241","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/ghe3\/8585241","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/ghe3\/8585241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T18:52:26Z","timestamp":1773773546000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/ghe3\/8585241"}},"subtitle":[],"editor":[{"given":"Hannah","family":"Wesley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/ghe3\/8585241"],"URL":"https:\/\/doi.org\/10.1155\/ghe3\/8585241","archive":["Portico"],"relation":{},"ISSN":["2054-4200","2054-4200"],"issn-type":[{"value":"2054-4200","type":"print"},{"value":"2054-4200","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"article-number":"8585241"}}