{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T07:25:10Z","timestamp":1775287510284,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"vor","delay-in-days":92,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acute cholangitis is a life\u2010threatening condition that requires prompt biliary drainage, typically achieved through endoscopic retrograde cholangiopancreatography (ERCP). However, data on outcomes of procedures performed outside of regular working hours remain limited. This study evaluates the safety and efficacy of out\u2010of\u2010working\u2010hours ERCP for acute cholangitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of 83 patients who underwent out\u2010of\u2010working\u2010hours ERCP for acute cholangitis was conducted. Patients were categorized by cholangitis severity (mild, moderate, and severe) and procedure timing (&lt;\u200912, 12\u201324, and 24\u201348\u2009h). Outcomes assessed included procedural success, complications, and clinical results. Multivariate logistic regression was used to identify predictors of prolonged hospitalization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the patients, 14.5% had mild, 19.3% moderate, and 66.3% severe cholangitis. Median time to procedure was shorter in severe cases (6.0\u2009h) than in mild (13.5) and moderate (14.5) cases (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.016). Technical success was 100%, with 91.6% receiving stents or nasobiliary drains. Complications occurred in 6%, and mortality (3.6%) was limited to severe cases. Early intervention (&lt;\u200912\u2009h) significantly reduced prolonged hospital stays (&gt;\u200915 days,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Out\u2010of\u2010working\u2010hours ERCP was associated with high technical success and a low complication rate in this cohort. Out\u2010of\u2010working\u2010hours ERCP achieved high rates of successful biliary drainage with an acceptable safety profile, and ERCP performed within 12\u2009h was independently associated with a lower risk of prolonged hospitalization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/grp\/2344299","type":"journal-article","created":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T06:41:45Z","timestamp":1775284905000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["ERCP Performed Out\u2010of\u2010Working Hours Is Effective and Reliable for the Treatment of Acute Cholangitis"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5952-2706","authenticated-orcid":false,"given":"Kerem","family":"Kenarl\u0131","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3914-7531","authenticated-orcid":false,"given":"B\u00fclent","family":"\u00d6demi\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3660-7237","authenticated-orcid":false,"given":"Dilara 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