{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:57:06Z","timestamp":1791374226253,"version":"4.3.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":279,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Food Science"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    This study evaluated the molecular, physicochemical, antioxidant, color, and colloidal characteristics of stevia\u2010sweetened aguaymanto (\n                    <jats:italic>Physalis peruviana<\/jats:italic>\n                    L.) nectar under 10 processing\u2010formulation conditions combining ultrasound power (0\u2013600\u2009W), treatment time (0\u201315\u2009min), and stevia concentration (0%\u20130.4%). Surface\u2010enhanced Raman spectroscopy (SERS) coupled with principal component analysis (PCA) was integrated with conventional physicochemical, antioxidant, CIELAB color, and particle\u2010characterization analyses. The citrate\u2010reduced AgNP substrate exhibited a surface\u2010plasmon\u2010resonance maximum at approximately 408\u2009nm, a\n                    <jats:italic>Z<\/jats:italic>\n                    \u2010average diameter of 42.6 \u00b1 6.3\u2009nm, and a zeta potential of \u221237.8 \u00b1 3.6\u2009mV. Significant differences were observed among treatment combinations (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05), with T9 (600\u2009W, 15\u2009min, 0.4% stevia) exhibiting the most favorable overall instrumental profile. Particle size decreased from 980\u2009nm in the untreated control to 270\u2009nm in T9, whereas the absolute zeta potential increased from \u221218.2 to \u221237.8\u2009mV and the PDI decreased from 0.49 to 0.21. T9 also showed the highest antioxidant, phenolic, flavonoid, and DCPIP\u2010reactive vitamin C responses. SERS revealed treatment\u2010dependent changes in characteristic bands at approximately 495, 1007, 1388, and 1613\u2009cm\n                    <jats:sup>\u22121<\/jats:sup>\n                    , whereas PCA differentiated the treatment combinations according to their integrated molecular and biochemical profiles. Because ultrasound power, treatment duration, and stevia concentration were varied concurrently, the observed responses cannot be attributed independently to individual factors; therefore, T9 is considered the best performing combined condition rather than a statistically optimized formulation. Overall, integrating SERS and chemometrics with conventional quality measurements provides a promising analytical framework for evaluating processing\u2010induced changes in functional fruit beverages. Further factorial optimization, chromatographic validation, microbial and storage assessment, and sensory evaluation are required before industrial application.\n                  <\/jats:p>","DOI":"10.1155\/ijfo\/2312352","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:39:46Z","timestamp":1791373186000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Integrated SERS and Chemometric Characterization of Ultrasound\u2010Induced Quality Changes in Stevia\u2010Sweetened Aguaymanto (\n                    <i>Physalis peruviana<\/i>\n                    L.) Nectar"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2234-6148","authenticated-orcid":false,"given":"Betzabeth Br\u00edgida Huam\u00e1n","family":"Estrada","sequence":"first","affiliation":[{"name":"Professional School of Agroindustrial Engineering Universidad Nacional Jos\u00e9 Mar\u00eda Arguedas  Andahuaylas Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7168-1742","authenticated-orcid":false,"given":"Franklin Or\u00e9","family":"Areche","sequence":"additional","affiliation":[{"name":"Professional School of Agroindustrial Engineering Universidad Nacional de Huancavelica  Acobamba Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2422-6250","authenticated-orcid":false,"given":"Peter Llimpe","family":"Perez","sequence":"additional","affiliation":[{"name":"Professional School of Agroindustrial Engineering Universidad Nacional de Huancavelica  Acobamba Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7601-3049","authenticated-orcid":false,"given":"Norma Elvira Muguruza","family":"Crispin","sequence":"additional","affiliation":[{"name":"Faculty of Bromatology and Nutrition Universidad Nacional Jos\u00e9 Faustino S\u00e1nchez Carri\u00f3n  Huacho Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6077-4409","authenticated-orcid":false,"given":"Jorge Luis Rojas","family":"Paz","sequence":"additional","affiliation":[{"name":"Faculty of Bromatology and Nutrition Universidad Nacional Jos\u00e9 Faustino S\u00e1nchez Carri\u00f3n  Huacho Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7038-6488","authenticated-orcid":false,"given":"Fiorella Victoria Luperdi","family":"Rios","sequence":"additional","affiliation":[{"name":"Faculty of Bromatology and Nutrition Universidad Nacional Jos\u00e9 Faustino S\u00e1nchez Carri\u00f3n  Huacho Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7407-4385","authenticated-orcid":false,"given":"Jacqueline Roxana Rea\u00f1o","family":"Rivera","sequence":"additional","affiliation":[{"name":"Department of Food Engineering Faculty of Fisheries and Food Engineering Universidad Nacional del Callao  Callao Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3305-0755","authenticated-orcid":false,"given":"Tania Jakeline Choque","family":"Rivera","sequence":"additional","affiliation":[{"name":"Professional School of Food Industries Engineering Universidad Nacional de Juliaca  Juliaca Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1245-8137","authenticated-orcid":false,"given":"Genaro Christian Pesantes","family":"Arriola","sequence":"additional","affiliation":[{"name":"Department of Food Engineering Faculty of Fisheries and Food Engineering Universidad Nacional del Callao  Callao Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6997-4290","authenticated-orcid":false,"given":"Carmen","family":"del Pilar Alvarez Quinteros","sequence":"additional","affiliation":[{"name":"Faculty of Bromatology and Nutrition Universidad Nacional Jos\u00e9 Faustino S\u00e1nchez Carri\u00f3n  Huacho Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,7]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.29312\/remexca.v16i5.3682"},{"key":"e_1_2_13_2_2","first-page":"169","article-title":"In Situ Morphological Characterization of 34 Accessions of Physalis peruviana L. 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