{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T08:14:53Z","timestamp":1788077693947,"version":"build-2784847793"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"vor","delay-in-days":241,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Hypertension"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Hypertension (HT) is associated with vascular dysfunction, chronic low\u2010grade inflammation, and increased arterial stiffness, all of which contribute to elevated cardiovascular risk. Lifestyle\u2010based interventions incorporating nutritional and exercise strategies may provide complementary vascular benefits. This study investigated the effects of chicken protein hydrolysate supplementation, administered alone or combined with concurrent training (CT), on arterial stiffness, blood pressure (BP), inflammatory markers, and physical fitness in adults with HT. In this randomized controlled trial, adults with HT who completed the study were included in the analysis: control (CON, n\u2009=\u200912), chicken protein hydrolysate supplementation alone (PRO, n\u2009=\u200910; 28 g\/day), and supplementation combined with CT (PRO\u2009+\u2009CT, n\u2009=\u200912) following the 8\u2010week intervention. BP, brachial\u2013ankle pulse wave velocity (baPWV), high\u2010sensitivity C\u2010reactive protein (hs\u2010CRP), and physical fitness outcomes\u2014including peak oxygen consumption (V\u0307O\n                    <jats:sub>2<\/jats:sub>\n                    peak) and upper\u2010 and lower\u2010body muscular endurance\u2014were assessed at baseline and postintervention. Significant group\u2009\u00d7\u2009time interactions were observed for baPWV (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01), hs\u2010CRP (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01), V\u0307O\n                    <jats:sub>2<\/jats:sub>\n                    peak (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01), and upper\u2010 and lower\u2010body muscular endurance (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01). Both PRO and PRO\u2009+\u2009CT demonstrated greater reductions in baPWV compared with CON (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05). Significant reductions in hs\u2010CRP were observed in both PRO and PRO\u2009+\u2009CT groups (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01); however, only PRO\u2009+\u2009CT demonstrated a significantly greater reduction compared with CON (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05). Improvements in V\u0307O\n                    <jats:sub>2<\/jats:sub>\n                    peak and muscular endurance occurred exclusively in the PRO\u2009+\u2009CT group (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01), whereas changes in BP were modest across intervention groups. Chicken protein hydrolysate supplementation, particularly when combined with CT, was associated with improvements in arterial stiffness, while the combined intervention further improved inflammatory status and physical fitness outcomes. These findings suggest a potential role for combined nutritional and exercise\u2010based lifestyle interventions in improving vascular function in adults with HT.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial Registration:<\/jats:bold>\n                    Thai Clinical Trials Registry: TCTR20251210008\n                  <\/jats:p>","DOI":"10.1155\/ijhy\/8962082","type":"journal-article","created":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T07:47:21Z","timestamp":1788076041000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Chicken Protein Hydrolysate Supplementation Alone or Combined With Concurrent Training on Arterial Stiffness in Adults With Hypertension: A Randomized Controlled Trial"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7728-0192","authenticated-orcid":false,"given":"Piyaporn","family":"Tumnark","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3971-4809","authenticated-orcid":false,"given":"Sarunrat","family":"Hirunrattanathum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pakaporn","family":"Sathalalai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6442-7391","authenticated-orcid":false,"given":"Tantawan","family":"Pirak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8859-3899","authenticated-orcid":false,"given":"Jatuporn","family":"Phoemsapthawee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,30]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1113\/JP273043"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11010172"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/jch.14448"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.2174\/157340211001141111160957"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.117.09097"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4732987"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.18433\/jpps29872"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2009.05.003"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S524495"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)01225-8"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jash.2018.01.004"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-014-0272-9"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/17461391.2014.955129"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.23736\/S0022-4707.20.11222-2"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jesf.2019.03.001"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2020.104164"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.12965\/jer.2244416.208"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu17213358"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.70984"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.33448\/rsd-v11i11.33353"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-019-09879-3"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fochx.2021.100181"},{"key":"e_1_2_11_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/1750-3841.16077"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells11081372"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu10091295"},{"key":"e_1_2_11_26_2","first-page":"903","article-title":"Angiotensin-I Converting Enzyme (ACE) Inhibitory Peptides From Chicken Skin Gelatin Hydrolysate and Its Antihypertensive Effect in Spontaneously Hypertensive Rats","volume":"26","author":"Sarbon N. 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