{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:30:23Z","timestamp":1773009023423,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":309,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Microbiology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:italic>Salmonella<\/jats:italic>\n                    Typhi is the causative agent of typhoid fever, a notifiable disease characterized by prolonged fever and gastrointestinal symptoms that may worsen and lead to death. This study was aimed at determining the epidemiological profile of typhoid fever based on clinical cases treated between 1999 and 2018 at the Evandro Chagas Institute, located in the state of Par\u00e1, Brazil. A total of 683 cases were analyzed, confirmed through PCR, stool culture, or blood culture. The findings revealed a consistent annual pattern in the number of reported cases, with the highest incidence occurring between June and November. The majority of affected individuals resided in the municipality of Bel\u00e9m, were male, had low levels of formal education, and were predominantly students. The age range of affected individuals varied from 1 to 88 years, with the majority of cases occurring in adults aged 20\u201359 years. Most cases occurred in urban areas with brick housing, biological septic tanks, dry soil, regular garbage collection, and access to public water supplies. Consumption of potentially contaminated foods, especially a\u00e7a\u00ed, was identified as a probable source of infection. The most frequently reported symptoms included fever, headache, diarrhea, chills, abdominal pain, nausea, vomiting, myalgia, and asthenia. These findings highlight the need to expand knowledge about the still limited epidemiology of typhoid fever in this region in order to support the implementation of effective control and prevention strategies.\n                  <\/jats:p>","DOI":"10.1155\/ijm\/3747557","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:13:39Z","timestamp":1762431219000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of the Epidemiological Profile of Typhoid Fever in the State of Par\u00e1 Between the Years 1999 and 2018"],"prefix":"10.1155","volume":"2025","author":[{"given":"Danielle Vieira Pina","family":"de Carvalho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8530-4411","authenticated-orcid":false,"given":"Anderson Nonato","family":"do Rosario Marinho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1385-7540","authenticated-orcid":false,"given":"Daniela Cristiane","family":"da Cruz Rocha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,6]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy846"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.108109"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2019.113432"},{"key":"e_1_2_9_4_2","unstructured":"Centers for Disease Control and Prevention (CDC) Vaccination 2019 Accessed May 1 2024.https:\/\/www.cdc.gov\/typhoid-fever\/typhoid-vaccination.html."},{"key":"e_1_2_9_5_2","unstructured":"Brasil. 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