{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T13:03:21Z","timestamp":1784811801753,"version":"3.55.0"},"reference-count":94,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":203,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Microbiology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    A biosurfactant\u2010producing fungal strain,\n                    <jats:italic>Exophiala spinifera<\/jats:italic>\n                    CSF123, was isolated from cashew oil\u2010contaminated soil. Internal transcribed spacer sequencing followed by phylogenetic analysis revealed that the isolated fungus shared 98.42% similarity with\n                    <jats:italic>E. spinifera<\/jats:italic>\n                    CBS66.76. The biosurfactant molecule, named ES\u2010414, produced by the fungus was purified to homogeneity by HPLC, and subsequent electrospray mass spectrometric analysis showed that its neutral mass is 414\u2009Da. The molecule displayed remarkable antibiofilm activity. At concentrations of 15 and 80\u2009\n                    <jats:italic>\u03bc<\/jats:italic>\n                    g\/mL, ES\u2010414 showed 62.17% biofilm inhibition against\n                    <jats:italic>Candida tropicalis<\/jats:italic>\n                    and 66% inhibition against\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    , respectively. It also displayed significant antifungal properties against\n                    <jats:italic>C. albicans<\/jats:italic>\n                    ,\n                    <jats:italic>C. tropicalis<\/jats:italic>\n                    ,\n                    <jats:italic>Candida glabrata<\/jats:italic>\n                    ,\n                    <jats:italic>Candida parapsilosis<\/jats:italic>\n                    , and\n                    <jats:italic>Candida krusei<\/jats:italic>\n                    . ES\u2010414, in a dose\u2010dependent manner, inhibited the quorum sensing activity of\n                    <jats:italic>Chromobacterium violaceum<\/jats:italic>\n                    . Thermogravimetric analysis of ES\u2010414 indicated that the molecule remains stable up to 240\u00b0C. Detailed structural characterization using GC\u2010MS, FTIR, UV\u2010visible spectroscopy, elemental analysis, Molisch test, TLC analysis, and solubility studies indicated that ES\u2010414 is a glycolipid\u2010like molecule.\n                  <\/jats:p>","DOI":"10.1155\/ijm\/5630530","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T12:35:02Z","timestamp":1784810102000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Glycolipid\u2010Like Biosurfactant Molecule Derived From an\n                    <i>Exophiala spinifera<\/i>\n                    Strain With Significant Antibiofilm, Antifungal, and Antiquorum Sensing 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