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CAUTI can be caused by antimicrobial\u2010resistant and biofilm\u2010forming microorganisms, resulting in recurrent and persistent infections. This study is aimed at analyzing the pathogens, antimicrobial sensitivity patterns, and biofilm\u2010forming capabilities of CAUTI isolates in two referral hospitals in Yogyakarta, Indonesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A cross\u2010sectional study was conducted on 71 patients with indwelling urinary catheters from October 2022 to March 2023. Urine specimens were collected aseptically and cultured. Microorganisms were identified and tested for antimicrobial susceptibility using Vitek 2, CHROMagar, and broth microdilution. Biofilm\u2010producing bacteria were identified by microtiter plate assay (MTPA), and selected urinary catheters were examined by scanning electron microscopy (SEM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 71 urine specimens from patients with indwelling latex\u2010urinary catheters resulted in 49 bacterial isolates and 28 yeasts identified.\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      ,\n                      <jats:italic>Acinetobacter baumannii<\/jats:italic>\n                      , and\n                      <jats:italic>Candida albicans<\/jats:italic>\n                      were the most frequent pathogens. Among Enterobacterales, 62.5% were extended\u2010spectrum\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2010lactamase (ESBL) producers, whereas 90% of\n                      <jats:italic>A. baumannii<\/jats:italic>\n                      and 20% of\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      isolates were carbapenem\u2010resistant. In contrast,\n                      <jats:italic>C. albicans<\/jats:italic>\n                      and\n                      <jats:italic>C. tropicalis<\/jats:italic>\n                      showed a fairly good level of sensitivity to various antifungals. Biofilm formation was observed in 91.8% of bacterial and in all\n                      <jats:italic>Candida<\/jats:italic>\n                      isolates. SEM examination of urinary catheter segments and tips revealed biofilm structures and microbial morphologies consistent with urine culture findings.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:italic>E. coli<\/jats:italic>\n                      ,\n                      <jats:italic>A. baumannii<\/jats:italic>\n                      , and\n                      <jats:italic>C. albicans<\/jats:italic>\n                      were the predominant CAUTI pathogens. Most isolates exhibited biofilm\u2010forming ability. Although bacteria showed high antibiotic resistance, yeasts remained relatively susceptible to antifungals.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/ijm\/8369920","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:04:32Z","timestamp":1784189072000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pathogen Characteristic of Biofilm\u2010Related CAUTI in the Intensive Care Unit"],"prefix":"10.1155","volume":"2026","author":[{"given":"Sayyidah Auliany","family":"Aminy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu Tholib","family":"Aman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4017-0499","authenticated-orcid":false,"given":"Ema","family":"Damayanti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0833-9258","authenticated-orcid":false,"given":"Ayu","family":"Rahayu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7402-5085","authenticated-orcid":false,"given":"Akhmad","family":"Taufiq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4424-7606","authenticated-orcid":false,"given":"Estelle","family":"Cateau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4628-5000","authenticated-orcid":false,"given":"Christine","family":"Imbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3463-4733","authenticated-orcid":false,"given":"Titik","family":"Nuryastuti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,16]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2010.11.005"},{"key":"e_1_2_12_2_2","volume-title":"DIAGNOSTIC for the Laboratory Sciences Introduction to","author":"Delost M. 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